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Re:Show HN: Mobi.css – A lightweight, flexible CSS framework... by simplify on Sunday September 04, 2016 @12:02AM (#12422615)
Are there any CSS frameworks nowadays that use flexbox instead of the float-grid model?
Re:Show HN: Mobi.css – A lightweight, flexible CSS framework... by xcatliu on Sunday September 04, 2016 @01:05AM (#12422816)
Bootstrap v4 provides an opinion to use flex box instead of the traditional grid.

http://v4-alpha.getbootstrap.com/getting-started/flexbox/

Re:Show HN: Mobi.css – A lightweight, flexible CSS framework... by jazoom on Sunday September 04, 2016 @12:22AM (#12422675)
I believe Foundation has a flexbox mode.

There's also this: http://flexboxgrid.com

I just use whatever I want and use LostGrid in flexbox mode for my grids.