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A comment on Software faults raise questions about the validity of brain studies. Parent comment

Re:Software faults raise questions about the validity of bra... by IanCal on Saturday July 02, 2016 @07:25AM (#12022142)
I think you're missing a key thing when talking about the activation estimation.

The measure is not blood flow, but the change in oxygenation of the blood, is it not? This does have issues but I think it's different from the issues you raised.

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Re:Software faults raise questions about the validity of bra... by Toenex on Saturday July 02, 2016 @08:34AM (#12022255)
You are right when you say the signal is BOLD and not flow directly. Flow regulation is a key component though. However, I don't think this negates my point. Oxygenation is being equated with brain activity. The approach is sensitive to BOLD signal changes that correlate with the input. I'm not a neuroscientist but I know many that would argue the brain is more complex than this and response are more complicated (what about areas of the brain that are on through out the experiment?)
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