My wife has had issues with almost everything she's been on. The only thing remotely acceptable to her has been the depo shot but she still had to deal with migraines, mood swings, considerable weight gain, and body hair. I finally said enough is enough and took the high road: I apologized for the last decade she accepted as "normal human life" and requested her to stop her contraceptives immediately. I called up the doctor and demanded a vasectomy. Problem solved. She's much happier now.

edit: the number of side effects for some of these female contraceptives are staggering and many women aren't aware of the entire scope of possibilities. I suspect most women are affected and don't realize it, just accepting it as normal because their friends have the same issues.