Anecdotally, I knew some people who took adderall in college that were not prescribed it and it seemed to cause them to have different behavior than myself. A similar situation, I would imagine, is how alcohol affects people differently. Maybe not physically, but you definitely see a wide range of actions and behaviors elicited among different individuals.
There are people who can take what are considered high therapeutic doses and feel very little effects because of the way their body metabolizes the chemical, which of course has nothing to do with whether they have ADHD or not.
7.5mg (15mg in half) is my usual dosage, but it's strong enough to fill me with the energy you'd expect someone on a high dosage to have. When I talk a full pill, it completely screws me over. Others can take 30mg and be completely fine.