Cities really, truly, have historically predominantly invented, produced and designed those things (including designing and paying for the factories seemingly in the country).

Not many medicine schools, pharma corps, research labs, car manufactures, tech companies, tv and movie studios, etc operating out of rural Idaho, or South Dakota, or Alabama, or what have you...

You do understand that cities build up around industry, right?

Historically speaking, they generally do. See forex Jane Jacobs: https://en.wikipedia.org/wiki/Jane_Jacobs#The_Economy_of_Cit...