If you consider it in terms of medicine. I would be afraid of performing any kind of surgery on myself, but I would be less afraid and ultimately trusting if a doctor did the same thing. If surgery is the wrong metaphor, how about theraphy or other forms of psychotherapy, mind change, anxiety reduction etc.

In other words, don't try it. The fear of insanity is probably a good fear if people think of doing it just for fun. But if the day comes when a doctor takes you in a trip, your fear will be less, and the doctor will know how to supervise you.

The key idea of this article is that research into psychedelics should be allowed and encouraged. Timothy Leary never advocated for people to try them for fun. Don't think of psychedelics as recreational things to try but as powerful medicine which needs trained professionals to administer.

What is "it" and why should you be afraid of losing "it"?