Also you can do some basic conversion from Tex to word using pandoc http://pandoc.org/
He had completely re-written huge chunks of my previous experience, changed the order of things to make me look like I had experience in areas that I definitely did not, and countless other minor changes. I couldn't believe it. His native language was definitely not English, so all of his changes had horrible spelling and grammar mistakes peppered in.
In the end I got the job, but only one other person had applied besides myself and the government agency the job was for desperately needed a body to fill a seat so I was kind of hired by default. Ended up being a crazy mess of a programming shop that I brought a bit of order to before leaving.
Even if you make sure your CV is a work of art, there's no guarantee it's going to be received in that state.
I usually keep mine in straight .txt format. If that doesn't work, I move on. I've usually investigated a number of places I might consider working and things like this help me narrow it down further.
For the vast majority of people posting here, we're working in departments that have nothing to do with HR, and HR's ability to read PDF files has no bearing on our (potential) boss's ability to read PDF files.
If one can choose, I guess that is one of the most important signals.
My CV (I think that's what you're all talking about - took a little while to work out you weren't actually resuming anything) is in LaTeX format. Places regularly got confused with being sent a PDF, and demanded Word instead, so I would just convert each page to a bitmap and load into a Word document as an image. Inelegant, but functional.
Back in the days when I was applying via job agencies, I even had one complain that there was something "wrong" with my Word document, as they couldn't work out how to edit any of it. I told them I thought that was a feature, not a bug.