The lapse here is not math, but rather spending lots of attention on abstract thought disconnected from any kind of reality check. Of course, there’s nothing inherently wrong with speculating sans evidence about the future, it’s generally a harmless hobby. In the best case it makes for fun SF novels. Convincing yourself, still without direct evidence, that your speculation reflects truth implies that something has gone off the rails in the reasoning process, however.
Using statistical analysis to understand real causal relationships in areas we have real data about is damn hard, and even plenty of people who are highly trained as statisticians screw up all the time. Academic fields like comparative politics (to take an example I spent a fair amount of time studying) are rife with poor conclusions drawn from bad analysis. The LessWrong folks are hardly unique in applying logic poorly. But they do tend to tackle more speculative questions and convince themselves more firmly of their conclusions (at least, such is my impression as an outsider).
Which is why every so often you'll get things like a physicist spending a couple months studying economics in their free time and deciding that they can now unlock the secret to economics which has eluded economists.
This xkcd comic sums it up well:
This can lead to your best guess based on available evidence being about as good at predicting the future as randomness in spite of all the apparent effort at making the predictions mathematically sound.
Also, this is one strange thing - any time someone asks us (the STEM crowd), "what will I ever use math for in my life?", the default answer seems to be, "it's about having more tools for thinking, and greater clarity of thought; it'll make you smarter". But then, some of us turn around and refuse to acknowledge that people who actually learn math and try to apply it may be getting those promised results. Whether it's LW people, programmers, engineers or scientists, the moment it matters, the default conclusion is that math gives nothing.