It probably isn't really progress in the sense the article writer thinks; juggling isomorphic representations is in some sense not "really" progress. But it can still be worth it for the practical improvements and potential didactic improvements. Perhaps if we had better education for QM with a better mathematical model, it would lead to less existential angst in the first place. I've seen Scott Aaronson trying to do some work on that front as well. In fact I'd consider it ironic if QM turns out merely to be slightly difficult and a hundred years of psuedo-philosophical babbling sourced from nothing more than a slanted view of relatively simple principles. I think some people will actually get upset if there is success in taking the mysticism away from QM....
Axioms of QM are few and clean. Sure, playing around them may be interesting. And if someone found its alternative formulation, more fundamental theory or anything - it would be great.
But (looking at the history of science) I see that the search of mathematical beauty sometimes leads to great discoveries; trying to satiate one's naive intuitions - rarely.
As someone who is bad at math and physics, the complaints don't seem all that different than first-year students scoffing at imaginary numbers, or centrifugal force. You don't "get it" -- so what? Why should the universe be easy to understand? QM just seems like more of the same.
People could handle heliocentricity, then the galaxy, then the universe, but for whatever reason, QM is just a bridge too far. Too weird, I guess.
One can shrug and say, we know what we need for computations. But a fairly fundamental theory should be cleaner. Of course, there is a perfectly simple theory (Bohm's) involving Schrodinger's equation and a guiding equation for particles that has all of this quantum formalism derivable from its dynamics.
A paper by Bell that goes into this point more clearly than I can articulate: http://www.tau.ac.il/~vaidman/IQM/BellAM.pdf
Sure, modeling decoherence is not always easy. (And, 'collapse' is often a nice simplification for practical purposes.)
Now, this can be rectified by using many worlds, for example. Particularly, integrating out the wave function to get a mass density on 3-space (non-relativistic version) does produce a valid theory which has multiple realities whose evolutions internally would appear to have single outcomes even when that is not actually true. Fuzzy tv reception with multiple overlapping channels is the mental model here.
However, that is not just decoherence. One has to add something. And the question is, why choose a theory that denies the truth of our common experience in such a fundamental way when one does not need to do so?
Pilot-wave theory is, subjectively, very simple and natural. It is not epicycles upon epicycles. In fact, quantum theory practically screams out for it with the existence of the probability current and the many insights that that current drives. There are at least 5 very distinct ways to derive pilot-wave theory from quantum notions.
One last thing to ponder. Wave functions are defined on the configuration space of the particles. The specific space is crucial to defining the evolution operator. Fermions and bosons emerge naturally by considering the configuration space of unlabeled particles.
But if you have no particles, why is a configuration of them useful at all?