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Re:Metformin as a Geroprotector (2011) by dghughes on Tuesday December 08, 2015 @12:26PM (#10697838)
Calories restriction as in Calorie Restriction with Optimal Nutrition aka CRON seems promising more than just restricting calories.

On BBC Michael Mosley has some interesting segments about CRON and its help reducing the levels of the IGF-1 hormone.

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