Metformin as a Geroprotector (2011)

Re:Metformin as a Geroprotector (2011) by rfreytag on Tuesday December 08, 2015 @11:36AM (#10697422)

Your discussion of the motivation for the metformin research is intriguing - thanks. NCI has funded human trials based on human epidemiological studies to further examine metformin's possible impact on cancer: (April 2015) http://www.cancer.gov/about-cancer/causes-prevention/researc...

Calorie restriction support was recently undermined by a NIA study. The conflict between the NIA and Wisconsin study is summarized by TIME here: http://healthland.time.com/2012/08/29/want-to-live-longer-do...

The teams are supposed to be working on a joint study to resolve their differing results.

EDIT: I have seen Dr. Mosley's BBC documentaries and they pre-date the recent CRON results. His HIIT segment is also very interesting. Not dismissing any of it - just not the slam-dunk that it seemed at first.

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Re:Metformin as a Geroprotector (2011) by dghughes on Tuesday December 08, 2015 @12:26PM (#10697838)

Calories restriction as in Calorie Restriction with Optimal Nutrition aka CRON seems promising more than just restricting calories.

On BBC Michael Mosley has some interesting segments about CRON and its help reducing the levels of the IGF-1 hormone.

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