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Re:An 80-Year-Old Prank Revealed, Hiding in the Periodic Table by jakejake on Wednesday November 25, 2015 @01:54PM (#10628839)
In the US saying "Peee Yooo" is often times combined with holding your nose. Sometimes each word is stretched for dramatic effect "Peeeeeuuueeee Yoooooooooo!"

It's somewhat of a children's expression for "that stinks", although adults use it to be funny.

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