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Re:Prescription painkiller deaths fall in medical marijuana ... by lagadu on Friday November 06, 2015 @07:14AM (#10519053)
I agree for this particular scenario but saying you'd rather use a plant than an opioid when some plants (like opium!) produce the same effects is disingenuous.

Something being a plant doesn't make it automatically better or worse than something artificial, otherwise we'd all be taking some nice nightshade tea instead of aspirin.

Re:Prescription painkiller deaths fall in medical marijuana ... by Spooky23 on Friday November 06, 2015 @09:42AM (#10519665)
I think you're reading into it a little too deeply. The point isn't to chew on a random leaf or avoid medicine.

We're in a situation where many people with chronic pain are handed marginally effective, dangerous and highly addictive painkillers, when they could literally grow a more effective and less dangerous pain control medicine in their backyard.

I had a severe back problem that led to a spinal fusion at age 25. I don't react well to most of the painkillers, so my only relief from excruciating pain (to the point where rolling over at night would wake me up) was motrin & hot towels. No idea if marijana would have helped me, but if it can help others basic humanity should compel us to legalize it.

Re:Prescription painkiller deaths fall in medical marijuana ... by MichaelGG on Friday November 06, 2015 @02:16PM (#10521360)
"Marginally effective"? How is e.g. oxymorphone or fentanyl only marginally effective? Excruciating pain and you were using ibuprofen? Why not even hydrocodone? Or if you wanted to grow it, grow poppies and extract the opium? Only difference is that weed grows a bit easier and requires a bit less harvesting work.

(Not to mention pot seems to dull intelligence; opiates do not.)

Re:Prescription painkiller deaths fall in medical marijuana ... by subnaught on Friday November 06, 2015 @03:34PM (#10521831)
I up-voted you because it's a fair question, but the grand-parent is absolutely right: there are plenty of cases where opioids are marginally effective. The management of chronic pain in particular is problematic because opioid tolerance can develop in as little as two weeks. In addition, some people have paradoxical reactions to opioids, i.e. increased pain (http://www.ncbi.nlm.nih.gov/pubmed/21412369). Finally, the side effects of high-dose opioids are no joke.
Re:Prescription painkiller deaths fall in medical marijuana ... by joslin01 on Friday November 06, 2015 @03:41PM (#10521878)
Marginally effective because it creates a dependence that ceases to become as effective as the onset and you merely end up with an addiction.

Marijuana, on the other hand, produces consistent highs and its effects reach deeper than mere pain relief though it's good for that too. Pot does seem to dull intelligence because it slows people down. This is not a sign of loss of intelligence however. In fact, the real culprit behind dulling of intelligence is alcohol.

----

In terms of marijuana and its effects on brain cells, or neurons, there is little evidence to suggest that any of the active ingredients in the marijuana plant administered at doses appropriate for human consumption have neurotoxic effects.

This is in direct contrast to alcohol, where the body’s digestive process creates metabolites such as acetaldehyde and other “reactive oxygen species” which are toxic to the brain and other cells in the body. This is why you have a hangover, after drinking large quantities of alcohol.

------

- http://www.drugpolicy.org/blog/does-marijuana-kill-brain-cel...

Re:Prescription painkiller deaths fall in medical marijuana ... by DanBC on Friday November 06, 2015 @03:30PM (#10521814)
Opiates get misused for a lot of pain when they're not really suitable for that particular type of pain.

For many people opiates are marginally effective because they were misprescribed.

Re:Prescription painkiller deaths fall in medical marijuana ... by Spooky23 on Friday November 06, 2015 @10:05PM (#10523488)
I was in PT for 2 years. I had to function during that period.

I was given hydrocodone, which dulled things and made me nauseous. The stronger stuff worked better, but left me exhausted.

It was easier to deal with pain.

I have no idea about marijuana. It's illegal to study it, so there are few facts available. Personally, I've seen a few people get hooked on opiates without any intention of abuse. All my pothead friends from college seem to have suffered no ill effect.

Re:Prescription painkiller deaths fall in medical marijuana ... by MichaelGG on Saturday November 07, 2015 @01:49PM (#10525761)
I'm sorry you had that reaction. It really must suck to be one of those that can't handle opiates (sincerely; my mom can't either).

Due note that the side effects do release over time in some people. For instance one patient I'm familiar with had an adverse reaction to hydrocodone frequently (1:1 to 1:3). But within a year it was closer to 1:50 and years later is around 1:200. There are other options that are more powerful and have less side effect. Combining with an anti nausea med seems to work (dimenhydrinate (Dramamine)).

I've read at least one study that showed improved cognitive due to opiates (from the pain relief). Unfortunately I can't find it right now (but I now get the point of a bookmarking service).

Addiction itself isn't that big of a deal. If the user doesn't want to be addicted, there easy ways to slowly get off. Take time, there's no rush. It's only the legal and financial aspects that make it problematic. If a doctor gives someone half a gram of hydrocodone for pain, they should be legally obligated to provide significantly more over time in case the patient starts to suffer any withdrawal symptoms. But doing so now, even admitting you took an extra one some night, gets you listed as a bad person. That's what needs fixing.

Re:Prescription painkiller deaths fall in medical marijuana ... by nommm-nommm on Saturday November 07, 2015 @07:37PM (#10526842)
"Addiction itself isn't that big of a deal. If the user doesn't want to be addicted, there easy ways to slowly get off. Take time, thes no rush. It's only the legal and financial aspects that make it problematic. "

Seriously? Im sorry but have you ever actualy met someone who developed an addiction to their pain meds!?

Re:Prescription painkiller deaths fall in medical marijuana ... by MichaelGG on Saturday November 07, 2015 @07:46PM (#10526866)
Yes I know many people. I also know some that OD'd off of crap "heroin". I know users that got promotions and high personal praise after switching to full-time OxyContin use.

I've met successful CEOs, VPs, and scientists that are addicted to opiates (Confirmed.) In your next professional interactions, look at everyone's pupils. You'll find some incredibly pinned. That's a pretty good sign.

Truth is things like OxyContin are often given to middle-upper class users and they suffer little downside (sex drive and constipation being the main things.) After you have enough income and supply the popular perception of addiction being a problem just disappears.

Re:Prescription painkiller deaths fall in medical marijuana ... by nommm-nommm on Sunday November 08, 2015 @03:27PM (#10529736)
This view is just absurd. Beyond comprehension.

You are aware of some people who function well with addiction so you assume that all addiction "isn't that big of a deal." BS. Go to a treatment facility and tell the patients (of all income levels) their opiate addiction "isn't that big of a deal."

I've meet many people (one an amputee, one great grandma in her 80) who have become addicted to their doctor prescribed medicine. All of which look like they have their lives together from the outside (and aren't having problems paying for their medicine) but their lives are being absolutely destroyed by opiates.

In the case of alcohol addiction there is even a word for this - "high-functioning alcoholic."

Just because you are able to function normally doesn't automatically make your addiction "not a problem" or doesn't mean it doesn't effect you in a negative way.

I'm not telling you that every addict is having their lives destroyed by addiction, but to assume that just because some don't means that all don't given enough income is preposterous.

"In your next professional interactions, look at everyone's pupils." No, thank you. I couldn't imagine wanting to do this.

Re:Prescription painkiller deaths fall in medical marijuana ... by MichaelGG on Monday November 09, 2015 @05:43AM (#10532263)
The majority of people I know that use, and the ones I meet online seem content to be addicted. Outside of funding issues and the occasional "what's sex drive again?" they seem to love it (on apart from when they must make a BM). It enables them to handle things they otherwise couldn't. I've met young kids with bone diseases leaving them vulnerable to repeated bone breakage. A fent lollypop later and they're beyond happy, and also have left pain behind.

I know professionals, drowning in whatever their work is. On behind or in debt. Opiates give them the optimism to face another day.

I'm honestly curious to know who is being destroyed by opiates, as in, what does destroyed mean? Outside of finances, legality, quality control, and other non-intrinsic, imposed issues.

Edit: If you'd like, my email's in my profile

Re:Prescription painkiller deaths fall in medical marijuana ... by mtdewcmu on Friday November 06, 2015 @03:33PM (#10521827)
Opioids are said to work poorly on nerve pain.
Re:Prescription painkiller deaths fall in medical marijuana ... by markamweb on Friday November 06, 2015 @03:09PM (#10521700)
Would love to learn more about how pot "seems to dull intelligence", do you have any sources?
Re:Prescription painkiller deaths fall in medical marijuana ... by MichaelGG on Friday November 06, 2015 @04:52PM (#10522306)
Personal usage a long time ago, and firsthand experience. I don't mean long-term (maybe, maybe not; irrelevant). I mean at high enough doses to get high or seek pain relief, pot doesn't seem to leave the user with their full intelligence.
Re:Prescription painkiller deaths fall in medical marijuana ... by GordonS on Friday November 06, 2015 @07:59AM (#10519191)
sigh, I knew someone would nitpick :)

Perhaps I should have been clearer; My point about it being simply 'a plant' is more that it can be grown at home by users - no need for heavy refinement, solvents, chemical processes or pharmaceutical companies.

Re:Prescription painkiller deaths fall in medical marijuana ... by milkytron on Friday November 06, 2015 @09:01AM (#10519458)
As time goes on though, as we can already see, specific components that make up the plant will be taken out and used on their own. This is already happening with THC and CBD with the plant being made into oils and concentrates. If cannabis becomes legal, I'm sure pharmaceutical companies will continue this trend in an aim to find the purest and most effective way to administer the drug, just like opioids today.
Re:Prescription painkiller deaths fall in medical marijuana ... by billmalarky on Friday November 06, 2015 @12:09PM (#10520500)
I don't claim to be an expert, but I've read time and time again the argument (from medicinal users) that pure THC in pill form doesn't really replicate the effects of using actual cannabis that well.

Mainly because there are a variety of different chemicals/cannabinoid at play when cannabis is ingested traditionally, not just one "purest" form of THC in high doses which is what you find in THC pills.

Not to say it can't be replicated/refined into pill form correctly, but my guess is it just won't be.

I don't think there will be a market for high quality pot-pills large enough to justify the massive investment needed to do it right when a better alternative (natural cannabis) already exists on the market and can be ingested in ways people generally enjoy (vapor, snacks, teas, etc).

That is, companies probably aren't going to increase revenues by increasing the quality of a product that already exists because the people who already use THC pills can't be "re-converted", and enough of the people who don't use THC pills, but are in the market for medicinal THC, probably won't make the switch.

Re:Prescription painkiller deaths fall in medical marijuana ... by GordonS on Friday November 06, 2015 @09:08AM (#10519490)
Yes, it's probably inevitable.

I can't find the link now, but I recently read a paper from Israel about how the effects of CBD acted in a bell curve when administered alone, but were much more linear when taken as part of a whole plant.

There are many cannabinoids, and they do often seem to work best when taken together.

Re:Prescription painkiller deaths fall in medical marijuana ... by nommm-nommm on Friday November 06, 2015 @10:20AM (#10519859)
I'd still rather take an aspirin than eat willow bark though. Acetylsalicylic acid has less side effects than salicylic acid and made it safer!

Isolating salicylic acid from willow bark and then a century later synthesizing acetylsalicylic from salicylic acid were all major achievements in medicine. It wasn't some sort of evil scheme.

I'm also guessing synthesizing acetylsalicylic in a lab is better than growing willow trees in almost every way. Less resource intensive, more environmentally friendly, cheaper, easier to scale, and faster production.

The "natural is always better" (for varying definitions or "natural", of course!) argument is silly.

"heavy refinement, solvents, chemical processes" are all just scare words. They don't mean anything useful. I can use those words to accurately describe cooking my dinner.

Re:Prescription painkiller deaths fall in medical marijuana ... by ihsw on Friday November 06, 2015 @12:15PM (#10520535)
The usage of "heavy refinement, solvents, and chemical processes" wasn't meant to scare, it was meant to inform -- those have costs associated to them, high costs.

The process of taking willow bark and turning it into a consumable product is not minimal, whereas taking cannabis and turning it into a consumable product is very minimal.

From a practicality standpoint, it is simply logical that medicine derived from cannabis is superior to willow bark.

Re:Prescription painkiller deaths fall in medical marijuana ... by thaumasiotes on Friday November 06, 2015 @12:39PM (#10520684)
> The process of taking willow bark and turning it into a consumable product is not minimal

How did you get this idea? Scrape some bark off a tree and steep it in hot water. You now have a consumable product.

Re:Prescription painkiller deaths fall in medical marijuana ... by the_watcher on Friday November 06, 2015 @01:13PM (#10520922)
Sure, but that doesn't prevent the basic plant from being distributed and consumed in the way it has for centuries.
Re:Prescription painkiller deaths fall in medical marijuana ... by anon4 on Friday November 06, 2015 @09:55AM (#10519739)
Just say "less addictive and with fewer side-effects". No need to have us go through all the levels of indirection, i.e. implications one must think of when you say "plant".
Re:Prescription painkiller deaths fall in medical marijuana ... by ska on Friday November 06, 2015 @09:11AM (#10519505)
Same could be said for opium.
Re:Prescription painkiller deaths fall in medical marijuana ... by Alex3917 on Friday November 06, 2015 @09:14AM (#10519518)
"when some plants (like opium!) produce the same effects is disingenuous."

I'm pretty sure poppy plants didn't evolve to produce massive amounts of Tylenol in order purposely poison people using the plant outside the religious beliefs of the ruling class.

Re:Prescription painkiller deaths fall in medical marijuana ... by Quinner on Friday November 06, 2015 @10:13AM (#10519820)
Wut.
Re:Prescription painkiller deaths fall in medical marijuana ... by cuckcuckspruce on Friday November 06, 2015 @11:30AM (#10520291)
Many drugs containing opiates are mixed with acetaminophen[1] by drug companies to reduce their abuse potential as acetaminophen is very toxic. The thought is that people that would abuse these medicines would think twice. All it really does is kill people[2] to the point where the government puts out information on how to spot someone going through such a poisoning.

[1] https://www.physicsforums.com/threads/why-some-opiates-mixed... [2] https://www.nlm.nih.gov/medlineplus/ency/article/002670.htm

Re:Prescription painkiller deaths fall in medical marijuana ... by facetube on Sunday November 08, 2015 @05:54PM (#10530371)
Even worse, acetaminophen has some serious difficulty with water solubility, so the people who really want the APAP out can get it done with no special equipment whatsoever. I wish combination drugs would just go away across the board, in all honesty.
Re:Prescription painkiller deaths fall in medical marijuana ... by facetube on Friday November 06, 2015 @10:33AM (#10519930)
Many common opioid formulations contain acetaminophen (paracetamol) in large amounts. If addiction develops, the acetaminophen will be the thing that kills you, via fulminant hepatic failure.
Re:Prescription painkiller deaths fall in medical marijuana ... by oafitupa on Friday November 06, 2015 @07:30AM (#10519099)
But removing the need for big pharmacological laboratories definitely makes it better. No more ridiculous prices, no more hidden corporate interests, etc. Just you and your plant, like nature "wanted" it to be.
Re:Prescription painkiller deaths fall in medical marijuana ... by fsloth on Friday November 06, 2015 @07:54AM (#10519172)
you and your plant, like nature "wanted" it to be

Most plants would prefer to kill us rather than get us high.

Re:Prescription painkiller deaths fall in medical marijuana ... by kjar on Friday November 06, 2015 @08:09AM (#10519230)
Plants that help humans are propagated by them.
Re:Prescription painkiller deaths fall in medical marijuana ... by pstuart on Friday November 06, 2015 @03:24PM (#10521778)
Re:Prescription painkiller deaths fall in medical marijuana ... by oafitupa on Friday November 06, 2015 @08:29PM (#10523192)
Plants can't "prefer", they are not conscious beings.
Re:Prescription painkiller deaths fall in medical marijuana ... by fsloth on Saturday November 07, 2015 @04:17AM (#10524251)
And a figure of speech has no shape nor figure :)
Re:Prescription painkiller deaths fall in medical marijuana ... by madaxe_again on Friday November 06, 2015 @10:39AM (#10519967)
Uh, although Aspirin is derived from salicylic acid, from the bark of willow trees, so...