Yep! I've used it at work on OSX for a variety of JavaScript, Clojure and ClojureScript projects for the past year and a half. There's some additional configuration that helps be more productive as with any new editor. Once I got that out of the way, it's been easy to work with. My LightTable configuration is at https://github.com/cldwalker/ltfiles

Disclaimer: I'm a Light Table maintainer