robbseaton
Re:Google suspending Parler from the Google Play store
on Friday January 08, 2021 @08:18PM (#25694428)
More than 200 BLM protests turned violent.
https://acleddata.com/2020/09/03/demonstrations-political-vi...
Re:Ask HN: Has anyone fixed their own bruxism?
on Saturday June 27, 2020 @07:31PM (#23665559)
Try magnesium.
Re:A Nearly Extinct Bootlegger's Corn Gets a Second Shot (2018)
on Wednesday June 17, 2020 @10:31PM (#23559212)
Hey, I love to trade seeds! I've got all sort of hot peppers. E-mail me at robb at rs dot io ? Other HNers welcome, too.
Re:Japan set to ban entry from the U.S. as early as next week
on Saturday March 28, 2020 @11:22PM (#22716092)
Previous experience with SARS is a better candidate for "primary determiner."
Re:Crystal 0.33
on Friday February 14, 2020 @10:23PM (#22332970)
n=1 but I am a Rubyist migrating to Julia, FWIW.
Re:ThinkPad Mods, Done Right
on Sunday February 02, 2020 @07:28AM (#22216645)
Re:FDA Approving Drugs at Breakneck Speed, Raising Alarm
on Saturday December 07, 2019 @02:33PM (#21732097)
Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design
The results for conventional fixed-sample randomized clinical-trial designs suggest that for terminal illnesses with no existing therapies such as pancreatic cancer, the standard threshold of 2.5% is substantially more conservative than the BDA-optimal threshold of 27.9%. However, for relatively less deadly conditions such as prostate cancer, 2.5% is more risk-tolerant or aggressive than the BDA-optimal threshold of 1.2%. We compute BDA-optimal sizes for 25 of the most lethal diseases and show how a BDA-informed approval process can incorporate all stakeholders’ views in a systematic, transparent, internally consistent, and repeatable manner.