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Tell HN: X reshapes the brain” et al. are meaningless statements

These types of posts are recurring.The most generic version of this would be "brain shaped by experience".If two people are instructed to lift their finger, but one is told to point up and the other to point down then bravo they've "reshaped their brains".These sorts of articles are always meaningless junk.No matter what experience is the subject of the article there will ALWAYS be changes to...

( Read More... | no comments | on HN )
Depending on the rigidity of your conscience you could whip up some buzzword laden project with "blockchain" written all over it.

Some suckers will throw money at that if you give it a colourful website with plenty of vague promises that you never have to deliver.

Re:The Cause of Depression Is Probably Not What You Think on Thursday January 26, 2023 @05:29PM (#34539806)
There is literally no useful information in this article.

It could be summed up as "everything people have been told is bullshit and we don't know what isn't".

What a waste of time.

So many words, so little information.
You need to:

1) Figure out the type of person who caused the trauma

2) Learn their psychology/world view (there are books on abusive personalities)

3) Learn to recognise them quickly

4) Have a plan to deal with them

5) Profit (you'll always have the upper hand)

By doing this you take away their ability to do anything. For some types this riles them up, which can be advantageous in eliminating the threat but also dangerous. You can plan for this.

Good luck.

Re:FDA to order Juul e-cigarettes off U.S. market on Wednesday June 22, 2022 @10:34AM (#31836518)
FWIW nicotine in cigarettes is only as addictive as it is because tobacco also contains short acting MAOIs (monoamine oxidase inhibitors - harmane and harmaline, the same ones combined with DMT) and other additives that relax the airways and increase nicotine absorption.

Smoking a cigarette is like taking a fast acting but short duration antidepressant along with a mild/moderate stimulant simultaneously, which has been specifically engineered to go from lungs to brain in the shortest time possible.

Switching to vaping from smoking has a transition period ranging from a few days to just over a week while the brain adjusts to receiving the nicotine much more slowly. Vaping relieves nicotine cravings, but at normal doses in an ex-smoker barely scratches the surface of the instant relief/rush delivered by a cigarette.

Nicotine itself and on its own is relatively harmless to an ex-smoker. But should still be avoided by non-smokers.

Most of the harm caused by cigarettes are related to the tobacco-specific nitrosamines found naturally in tobacco which are carcinogenic, combined with additional carcinogens and harmful compounds created when tobacco combusts.

That said many of the flavourings used in e-cigarettes are harmful to health, especially when heated. Most notably sucralose, which itself partially decomposes into carcinogenic compounds when heated to temperatures reached by vaping. But that's another problem, my main point is that nicotine is only about as harmful as caffeine when consumed alone outside the context of a cigarette.

Re:Ask HN: Amazon sharing data with Facebook/Meta? on Wednesday March 30, 2022 @10:39AM (#30855816)
Update: So I discovered numerous services were sending data directly to Facebook, using some form of hashed identifier, presumably a hash of my contact info.

The two big ones being Amazon and Uber.

Anyway I've decided to switch to a dumb phone in the near future and just stop using the internet once I've found offline replacements for everything I currently use the internet for.

It's just not worth it anymore.

Ask HN: Amazon sharing data with Facebook/Meta?

I have all tracking settings possible turned off on my devices, including in the Facebook and Amazon apps.Usually the ads shown to me are random, great!Except whenever I use the Amazon Android app, not long after Facebook starts showing me targeted ads based on products I've viewed on Amazon.For instance I was looking for gravel and other types of decorative stones for gardening purposes. Many...

( Read More... | 2 comments | 3 points | on HN )
Re:TikTok is scary good. It's digital crack on Saturday March 26, 2022 @11:20PM (#30817443)
Other platforms only look for similar content to what you've already seen. They don't take novelty into account.

If you like one picture of a dog on Instagram it'll just show you more dogs and you get bored. Watch a few YouTube videos about one topic and the algorithm gets fixated on it.

YouTube is so bad now that if you use it to listen to music the autoplay gets into an infinite loop of songs that sound near identical, it's torture if you don't already know what you want to see/hear.

In short the usual algorithms are tailored to find similar content only, rather than finding novel content several degrees of separation away from what the user has expressed interest in.

Re:Why aren’t there more dogs at the doctor’s office? on Sunday March 20, 2022 @02:42PM (#30745354)
Allergies.
Re:Ask HN: Where to Find Interesting People? on Friday March 18, 2022 @12:45AM (#30718817)
Define interesting.

If by interesting you mean people who enjoy the same topics of conversation as you do then pick a topic.

Figure out what people interested in that topic do, where do they go.

Go there.

We don't go to China for cheap labour.

We go for skills and manufacturing capacity & capability.

China has advanced so dramatically and the population so vast that they've essentially overtaken the West in nearly every category.

I think it was Tim Cook who said, when asked why the iPhone is made in China, that for every one American with the necessary engineering skills you could fill an entire football stadium with Chinese engineers.

We barely make anything ourselves in the West. At this point we're just shells of our former selves, totally dependent on China and to a lesser extent other countries.

Virtually everything has "Made in China" written on it, from your iPhone to that not-so-great random gadget you bought on Amazon.

Meanwhile we're perpetually distracted by inane nonsense fads/infighting and dimwitted celebrity bullshit.

The World is Made in China, we're just along for the ride.

Re:UK rejects opening borders to Ukraine refugees on Monday March 07, 2022 @11:34AM (#30589858)
To all the people assuming we're reducing immigration because of some kind of phobia.

The simple truth is we don't have anywhere for them to go.

We have a near permanent homeless population, with people living on the streets for years before a social housing vacancy becomes available.

Accepting an infinite number of immigrants would turn the entire country into a slum. We're in the middle of a massive housing crisis.

What are we supposed to do with them?

Re: on Thursday March 03, 2022 @11:04AM (#30542737)
Scrunching up the tissue into a ball creates gaps in the surface.

The only logical thing to do is fold to maintain proper contact.

Noobs.

Enzymes are proteins that accelerate chemical reactions.

Genetic engineering is already used to manufacture some chemicals by modifying the DNA of microbes to produce the necessary enzymes. The microbes then consume the precursor chemicals and synthesise the product.

Indeed every natural bioactive chemical is manufactured by proteins in the form of enzymes.

So the mRNA for the necessary enzymes could be given to a person, and their own cells would become short term chemical factories for their medication.

The problem is getting the cells to synthesise the right amount of a drug, and mRNA is quickly destroyed so would require repeated dosing just like regular drug administration. For something permanent CRISPR-Cas9 would be required to edit the actual DNA of the cells.

A DIY biohacker cured his lactose intolerance by engineering a virus to modify his cells to produce the lactase enzyme in his digestive tract. I think the results lasted several months in that case but could be wrong, may have been permanent. Video of the project on YouTube.

Re:A Drug to Cure Fear (2016) on Sunday February 13, 2022 @04:20PM (#30325793)
The hypothesis that blocking noradrenaline (norepinephrine) is the mechanism of action here doesn't make any sense.

In fact nothing about what the author states about noradrenaline makes any sense. It just doesn't work like that.

Re:Time Tracking for Freelance Developers on Friday January 21, 2022 @10:48PM (#30033259)
Time tracking is self sabotage.

It's better to estimate the hours required, quote for those hours and agree a completion date in advance.

With time tracking you're inviting unnecessary scrutiny and failing to establish work boundaries that can leave the client with no sense of beginning and end. It also leaves you constantly multitasking and bookkeeping.

If a client is insisting on time tracking it's probably because they're paranoid about getting ripped off or needing the insight into what they're paying for.

Upfront estimation with deadline gives them the peace of mind they need, establishes the boundaries and frees you to get on with the job.

If you underestimate do better next time, if you overestimate then great have a margarita.

This path leads to burnout.

You have three weeks to find a new hobby. Your challenge starts now.

In other news: grass is green and the sky is blue, who knew?
Tell that to my hair follicles.
I speak some French but no where near fluent. Native English.

I pronounce "oui" not as "we" but as you describe. The sound starts at the back of the tongue towards the throat and barely involves the lips, unlike "we" which starts with the lips.

Just an anecdote you might find interesting for whatever reason.

Re:Ask HN: How did you fix bugs before StackOverflow? on Tuesday November 23, 2021 @12:08PM (#29320270)
Same way as after StackOverflow.

A combination of thorough logging throughout the codebase at various levels of detail, one off print statements, then once it's narrowed down to a specific chunk of code reading it intently and finally if that doesn't work fire up a debugger and step through it.

Re:Tracking Crucial Metrics of Earth's Global Warming on Sunday November 21, 2021 @11:25AM (#29297403)
Website briefly flashes then disappears on mobile apparently.

Ask HN: Has Facebook always been this buggy?

Long story short over all these years I never bothered with Facebook. It turns out some hobby groups only exist on there, so I created an account about a week ago.I'm shocked at how buggy the Android app is for such a large tech company with so many years and so much money being thrown at engineers. I hear on HN about massive 6-7 figure salaries yet their main product barely works.Some of the...

( Read More... | 6 comments | 6 points | on HN )
Re:Ask HN: Anyone else tired of all your music? on Friday November 12, 2021 @05:34PM (#29205320)
Spotify in the early days used to be great for this. Their entire catalogue was browsable with fine grained genres. They ruined it and became useless for music discovery.

If Last.fm is still around that may be useful, they are/were great at finding similar artists so you could go to one artists page, click through similar artists a couple of times and find something fresh that you didn't know you liked.

It was also great because you could hook up your music player of choice via plugins to Last.fm and it would do a damn good job of regularly finding your next favourite artist/track on your profile page.

Like most things tech related the music realm only seems to get worse as time goes by.

Re:Ask HN: Can I believe in climate change, but not fear it? on Wednesday November 10, 2021 @02:32AM (#29172061)
Whatever floats your boat.
Maybe try the opposite. You can have too much of a good thing. Cover the screens, spend time outside, read a good book unrelated to tech, diversify your time.

If motivation were a battery you wouldn't try to recharge it and use it at the same time. It might get you a little more uptime but the stress leads to early failure.

Re:Ask HN: Do you play any mobile games? on Tuesday November 02, 2021 @08:41PM (#29089647)
I played Stardew Valley for a good while. As far as I can tell though mobile gaming is a failed concept overall. Pixel Dungeon is good if you're looking for a roguelike.

Other than those two it's all mind numbing one button auto scrollers, crappy money extraction attempts, and boredom. The games that actually look good usually suffer from the inadequate input method that is a touch without tactility.

There's a boat racing game that's pretty good too from the people that made Beach Buggy Racing. So I guess there's three games worth playing.

Re:Cheap antidepressant shows promise treating early Covid-19 on Thursday October 28, 2021 @08:28AM (#29025263)
Tricyclics (and tetracyclics) tend to be incredibly potent antihistamines, which may explain this.
Re:Ask HN: How do I regain my passion for programming? on Friday October 22, 2021 @09:21PM (#28964757)
You need to stop building things you don't enjoy building and which you have little to no interest in actually using. After that take as much time as necessary for something to strike your interest, possibly in a totally different domain (e.g., embedded systems instead of CRUD crap).

Once you reach that point tinker a little, not a lot. When you feel resistance take a break, never force yourself. Don't force yourself to write code you don't enjoy writing, find ways around it, at least initially. You need to avoid reinforcing the association between code and pain until you have a buffer of good experiences in your new domain.

It might be (probably will be) necessary to find a new career path in the meantime.

Good luck.

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