mcbain
mcbain on Hacker News
Posted by
mcbain on Thursday August 20, 2026 @03:12AM
from the datadoghq.com dept.
Posted by
mcbain on Monday March 23, 2026 @01:54AM
from the flightradar24.com dept.
Posted by
mcbain on Thursday March 19, 2026 @07:19AM
from the theguardian.com dept.
The former. It doesn't quite roll off the tongue, but with my (Australian) accent the difference is minor.
Yes, with MRI brain too. I was on 4/year, but that number is reducing as time goes on without recurrence.
I have multiple scans a year. "Scanxiety" is real.
Spot on. And dealing with false positives sucks.
One caveat is that regular PET isn't so good in the brain - there is so much metabolic activity that everything glows. So I get an MRI Brain to go with my regular full body PET/CT (cancer 5 years ago with recurrence 18 months later, currently NED).
Linde was definitely around as a distinct brand in Australia before they bought BOC in 2006, but since then as you said, they now just trade as BOC.
When have they ever claimed that?
As others pointed out, these are stage I trials and these are patients that have had other treatments already. In particular the melanoma patients had already had other immunotherapy - which is known to work for 50+% of cases - so this could help plugging the gap for the rest.
The testing here is not just that it is safe on skin, but the SPF test itself is done by slathering it on humans and exposing them to light to determine a rating.
Also the club scenes, with a bunch of regulars from Hellfire/Black Market, on Regent St. (Now a cafe supply store.)
Sadly Richard has now had recurrence. There is still hope for this treatment for others, and it likely extended his life, but it isn't happily ever after this time.
Posted by
mcbain on Friday May 23, 2025 @06:56AM
from the rachelbythebay.com dept.
No chemo. The entire idea of this regime is to hit the tumour with immuno to get the reaction. They want lots of tumour cells and for it to be "treatment naive" - Richard hadn't even had corticosteroids, which dampens immune.
Once they primed his system they excised as much as possible and kept the immuno going while doing a course of radiation.
Profs Long and Scolyer work with melanoma where chemo is rarely used these days.
It's easy for (say) AWS to terminate your EC2 instances. Do they also delete your DB backups? Delete your S3 buckets?
All of these incur costs. How hard a cap do you want?
There's a bunch of different immuno types for melanoma (and other cancers). That one is a combo of nivolumab (aka Opdivo) and relatlimab.
Nivo is used a lot for melanoma, also commonly in combo with ipi (ipilimumab, yervoy). Pembro (keytruda) is the other common one.
Anyway, any of these can have adverse effects so patients are closely monitored.
For me, my thyroid didn't like nivo much but recovered. But we stopped after a couple of cycles of ipi+nivo because I was starting to develop colitis. And more importantly it wasn't slowing development of my melanomas.
Posted by
mcbain on Tuesday June 11, 2024 @08:29AM
from the wired.com dept.
I get an MRI Brain every three months. I usually opt out of the piped music - mostly because it's either a bad choice by the radiology techs or tuned to a generically awful radio station - but the headphones lock into the head cradle so I use them with earplugs underneath. I close my eyes and tune out and try to not sleep (and twitch so they have to restart the capture).
Some of the pulse sequences are rhythmic and I find the entire thing somewhat meditative, but there are many other places I'd rather be.
The title here currently drops "Western" from the linked article and the start of the airport name - importantly this is the yet to be completed WSI not the existing SYD.
Posted by
mcbain on Thursday February 22, 2024 @04:55AM
from the themandarin.com.au dept.