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lloydarmbrust

I'm just asking if you've ever used one.

I don't want to assume, but if you've used one, you would understand the benefits are far greater than weight loss.

Yes. I've done it before with medical devices. Pharma is surprisingly similar, but there's more testing.
We've definitely been focused on the more important parts first. I just need one flight from SFO to Austin to fix this website issue.
The truth is a lot less exciting. We got into YC and registered the company name that night, and the domain name was available. The Ro connection was pointed out later. If we are forced to rebrand, we will be more thoughtful.
So cool! Hundreds of careers and even families came from OwnLocal!
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @11:35PM (#49545640)
I see what you did there, and I approve this joke.
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @11:34PM (#49545630)
Have you tried a GLP-1?
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @09:15PM (#49544797)
This is a really beautiful site. Thank you for sharing it.

I think the only thing that separates us is that we manufacture the drugs and probably own more of the supply chain than they do. But they're doing a much better job on the front end.

Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @09:09PM (#49544744)
She’s been doing supervised fine-tuning since 2017.
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @09:08PM (#49544731)
You seem to know a lot about this, and I was nodding along with a lot of your points as I was reading.

I was Stripe's first customer in 2010, so we solved the credit card processing issue :) it turns out that being in YC is good for more than just money.

You are right about HIPAA, everyone thinks this is much harder than it actually is, but GCP, OpenAI, Linq, everyone has given us a BAA.

We're definitely not trying to go after the market of people that are comfortable buying from Chinese suppliers and risking their health. When I built my mask factory, our masks were absolutely more expensive than Chinese masks, but what people were buying was a guarantee that it would meet certain filtration requirements. Some people are willing to pay for safety, but it's not important to everyone.

The only thing I really disagree with with you on is that this isn't a YC-scale company.

We are growing 56% compounded week -over-week, and I have every expectation we'll do $10 million this year, $100 million next.

We are making something that people are already buying and getting it to them in a safer, more cost-effective way.

Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @09:02PM (#49544695)
The dosing starts out surprisingly simple. The magic is in the feedback loop: asking the patient how they're feeling, if they're getting the effects they want, and then having their doctor review and approve a new dose.

Point taken that RUO people are just yoloing this, I was one of them. Now, I can tell you that having a doctor in the loop with my health is very helpful.

Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @08:55PM (#49544669)
Yeah. Armbrust Inc. It's me.
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @07:30PM (#49544034)
Building a startup, everything is important, but you do have to stack rank. This is getting to the point where it's probably the most important thing. And it won't take that long to fix.
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @07:29PM (#49544027)
I will reach out. Thank you!
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @07:29PM (#49544024)
We are co-manufacturing the API, and then we are bringing it in-house in the next 9 months.

The legal cutout that we have is on the personalization front, which is very well protected. The trick is that most compounders are not actually personalizing, and we are. Our feedback loop allows us to do real personalization on a week-by-week basis.

Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @07:22PM (#49543974)
My wife tells me all the time I sound like AI. I blame my childhood.
Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @07:21PM (#49543968)
Yes, we incorporated the business 10 weeks ago, and we've been focusing everything on the infrastructure of the actual product people are getting.

These messages are very helpful, though, to help motivate me to get our team to fix this, so I do appreciate it.

Re:Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s on Wednesday September 02, 2026 @06:44PM (#49543607)
Fair criticism. It is AI slop all the way down. The only thing we focused on was the clinical aspects of the onboarding and the technical ability to be able to legally write a prescription and make and ship drugs, which was very complicated. We were able to accomplish this in less than 10 weeks. But I have not had time to go through all the marketing, and I apologize.

Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s

https://ronanrx.com/

Hi HN,I’m Lloyd, one of two founders of RonanRx. We are building a vertically integrated pharmaceutical company with software for prescribing, telehealth, compounding, manufacturing, and delivery. We are starting with GLP-1s and peptides.The path to RonanRx is fairly unconventional. During the pandemic, I built one of the largest mask manufacturing factories in the US. We could make a million...

( Read More... | 83 comments | 13 points | on HN )
That's because the rails didn't really exist for hiring the kind of talent modern startups needed until recently. We've had about 10 developers in LATAM for 3-4 years and it's been a game changer for my companies.
This data set took me 2 years to compile but just recently seemed complete enough to post.
Yes! Use these: https://www.armbrustusa.com/products/armbrust-ear-savers

Screenshot this post and let support@ that I said to include a pack for free with your earloop replacement.

It wasn't optimized for mobile but is now... please LMK what you think!
great mask would recommend
Paul Graham
Thanks! Honestly didn't do this to directly sell masks... according to shopify we have made a whopping $248 from this post
Adding this to the feature list
Nice! Fixed
If it helps 100% of my grandparents are from Germany :) might be obvious by my last name.
hahaha got me on that one.

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