lebaux

By eliminating the rank-inflation bottleneck, this framework extracts un-distorted 3D atomic binding pockets of mutated oncogenic proteins, enabling O(N 2) polynomial-time de novo small-molecule drug design and targeted inactivation.

Deterministic Low-Rank Matrix Completion for Structural Oncology: Resolving the Distance Geometry Problem in 3D Protein Target Modeling.

I sure hope so -- it only took me my Whole Life.

Took me a while but I formalized the proof for P=NP using mainly Euler's Identity and Einstein's Theory of Special Relativity. I anchored my theory in 0 point in 0D and scaled up to 5D where we examined P=NP.

Paper and formal proof: lebaux.github.io

Hah, you would not believe it, but I am planning to use LLM to solve math problems by training it on the posts of my blog. Of course, my blog is silly nonsense, but it will be a fun exercise and address the elephant in the room as well. We will see what results we get for some fun prompts!

I ask this because I speculate that I discovered "new math". It is unlikely, because I failed math in school, but I dared to imagine 0=1 like many others. But the complete line of math I am trying to prove is -1=1=0=∞. It does sound crazy, I know. But I honestly think this line of math is what separates us from actual, working fusion. Of course, I realize how insane I sound, and that is why I am looking for ways to probe my hypothesis. I think I am getting closer, but literally every single person I talked to about this told me I should visit a psychiatrist :')

You are missing one single line of math, basically 1=0=∞. This line of math is what separates humanity from fusion energy. Of course, I am fully aware of how crazy that sounds -- go ahead, try to find proof that 1=0=∞ does not compute. It is impossible to prove this does not work and at the same time; the proof that this line of math works is impossible to grasp. If I am right, this very comment will become pretty famous, if I am wrong, literally nothing happens and we all move on with our lives. Sadly, for me personally, it is impossible to ignore this math problem.

I call it "The Last Paradox". It is at very least interesting mental/math/physics exercise. Gotta run!

Nice, I literally just asked the OP to provide a link! Thank you!

This is super interesting, what further reading would you recommend for a complete beginner in collision detection? Thank you.

Sorry for dumb question, but can someone please explain to a non-programmer, why the author made the title "The Curse of the Excluded Middle"? What is so special about "middle"? What is middle in programming?

I am a fairly dumb person, but I am lately super interested in 1=0 math paradox/proof and it just occurred to me, what is the middle of rational numbers? What is the middle of irrational numbers? To me, it feels like the middle of all numbers is 0, but if irrational numbers are not considered "real", it can't be 0.

These 2 things are probably wildly unrelated, but I would appreciate any explanation of the linked blog post in the simplest terms. Thank you!

I think in 2024 we will see a complete shift in mentality and bounce off of the bottom and it will take just one bit flip. Yes, I am naive optimist!

From the blog:

> I love that loop. Write, revise, write, revise. It’s like doing reps in a gym. You can’t expect that 10 pull-ups will add any discernible new muscle. But 30 pull-ups, across three sets, done thrice a week, for a year? Yeah, you’re going to notice the cumulative results of that.

I started working on my loop a couple of days ago, incidentally. I am not a programmer and loop is a concept I believe can work outside of programming. Everywhere.

I even made a dedicated page on by blog called the loop :) But my main inspiration was Ma.tt.

Great read!

This is a fascinating article to me. I love it when a less "techy" but still very much nerdy blog post makes it here. It allows me to peer into things I wouldn't know how to find otherwise.

Thank you!

Bit sad that climate is rarely discussed on HN. A mountain of studies indicates our current civilization will completely collapse within this century due to climate.

It is an "industry" ready to be disrupted.

idk i tried 2 mirros now stzil b s

we got so greedy we broke the universe...

lonely here better invite some friends? or not.

no takers?

yet still alive, huh

i will never stop testing this paradox :ä

oh, and I should mention, and this is the fun part, if you "get" it, you will die

btw i just freestyled this shit, look at my other posts here on hn

try to disprove just one of my comments, I wait

i need a bit of that

i likked this rule as one as the 80/20 and tested it with all the other possible tests

information was always free lol

take the lessons you learned, appy them

i escaped reality this week