ksolanki

I posted this because it had one very relevant statement (to me, since I am one of those who is being advised to take Vit D supplements) from the article:

"So, for the millions of Americans who take vitamin D supplements and the labs that do more than 10 million vitamin D tests each year, an editorial published along with the paper has some advice: Stop.

“Providers should stop screening for 25-hydroxyvitamin D levels or recommending vitamin D supplements and people should stop taking vitamin D supplements in order to prevent major diseases or extend life,” wrote Dr. Steven R. Cummings, a research scientist at the California Pacific Medical Center Research Institute, and Dr. Clifford Rosen, a senior scientist at the Maine Medical Research Institute. Dr. Rosen is an editor at The New England Journal of Medicine."

So if someone wants a “read receipt” they should pay, and the recipient should have the right to receive or not.

That should work to each party’s satisfaction.

What’s the solution if you are Gitlab? It takes revenues to sustain this. Is there a better model?

Yes, can’t we have an email equivalent of social graphs and interaction that can be driven by open standards?

I am sure people have thought about this.

All the Government needs to do is to enforce compliance to such standards.

I am a right hander but use my mouse with my left hand. Why? “Saving my right hand to play tabla (Indian hand drums)”.

In any case, over the years I have become very comfortable using mouse with left hand as a right hander.

I do not fully understand this, but isn’t this the story at the federal level as well?

There is a potential solution: how about an app like fortnite to charge the users 30% more and be transparent about it if they use the App Store to buy? Is that against the App Store TOS? There has to be a way for the costs to be made transparent so users can make an informed choice. It doesn’t have to be these large lawsuits?

I am not sure. My biggest driver has been to be in my death bed and having done nothing, having made no difference to the world. So I keep trying.

It will be drones owned by people, similar to kindles or echos. There is no fleet, no (or very few) drones shot down or stolen.

Every family will have a drone “pet” with sole purpose if delivering Amazon stuff, in this case literally.

Ok, now that we agree this is neat (I am impressed!), what’s the solution?

Google or not, what can help me discover the right recipe, the right content, the right answer to my coding error?

Search algorithms that keep “mutating” even randomly? Ranking system? What?

I agree that we are in a unprecedented situation but I am not sure that the regulations will just be “damned”.

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is global medical technology company that has developed a powerful retinal image analysis AI eye screening platform for detection of diseases. Eyenuk is on a mission to screen every eye in the world to detect and monitor life- and vision-threatening diseases including diabetic retinopathy, macular degeneration, glaucoma, cardiovascular and stroke risk, and Alziemer's disease.

Eyenuk's first product, EyeArt, is a fully autonomous (no doctor oversight needed) AI eye screening system for detection of diabetic retinopathy. Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and has completed prospective clinical trials for an FDA clearance. The results are exceptional: https://finance.yahoo.com/news/eyenuk-ai-eye-screening-syste....

You will join a passionate team at Eyenuk comprised of software and machine learning experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (machine learning, computer vision, deep learning)

jobs at eyenuk.com

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is global medical technology company that has developed a powerful retinal image analysis AI eye screening platform for detection of diseases. Eyenuk is on a mission to screen every eye in the world to detect and monitor life- and vision-threatening diseases including diabetic retinopathy, macular degeneration, glaucoma, cardiovascular and stroke risk, and Alziemer's disease.

Eyenuk's first product, EyeArt, is for fully autonomous AI eye screening system for detection of diabetic retinopathy. Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and has completed prospective clinical trials for an FDA clearance. The results are exceptional: https://finance.yahoo.com/news/eyenuk-ai-eye-screening-syste....

You will join a passionate team at Eyenuk comprised of software and machine learning experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (machine learning, computer vision, deep learning)

jobs at eyenuk.com

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is global medical technology company that has developed a powerful retinal image analysis AI eye screening platform for detection of diseases. Eyenuk is on a mission to screen every eye in the world to detect and monitor life- and vision-threatening diseases including diabetic retinopathy, macular degeneration, glaucoma, cardiovascular and stroke risk, and Alziemer's disease.

Eyenuk's first product, EyeArt, is for fully autonomous AI eye screening for detection of diabetic retinopathy. Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and has completed prospective clinical trials for an FDA clearance. The results are exceptional: https://finance.yahoo.com/news/eyenuk-ai-eye-screening-syste....

You will join a passionate team at Eyenuk comprised of software and machine learning experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (machine learning, computer vision, deep learning)

jobs at eyenuk.com

This is really amazing. Kudos to you for the initiative. Going through regulatory, IP, clinical etc. is hard but not that hard. We are going through this ourselves at our startup, and it is daunting and rewarding at the same time. I am happy to share notes should you like.

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is global medical technology company that has developed a powerful retinal image analysis AI eye screening platform for detection of diseases. Eyenuk is on a mission to screen every eye in the world to detect and monitor life- and vision-threatening diseases including diabetic retinopathy, macular degeneration, glaucoma, cardiovascular and stroke risk, and Alziemer's disease.

Eyenuk's first product, EyeArt, is for fully autonomous AI eye screening for detection of diabetic retinopathy. Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and has completed prospective clinical trials for an FDA clearance. The results are exceptional: https://finance.yahoo.com/news/eyenuk-ai-eye-screening-syste...

You will join a passionate team at Eyenuk comprised of software and machine learning experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (machine learning, computer vision, deep learning)

Would welcome anyone who wants to join our hands: have a young family? Great! Need a visa? We'll do everything legally possible to get you one.

jobs at eyenuk.com

Unless you want a promotion (from what I understand). And most want a promotion or change in job responsibilities in 10 years.

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is global medical technology startup company that has developed a powerful retinal image analysis AI eye screening platform for detection of diseases. Eyenuk is on a mission to screen every eye in the world to detect and monitor life- and vision-threatening diseases including diabetic retinopathy, macular degeneration, glaucoma, cardiovascular and stroke risk, and Alziemer's disease.

Eyenuk's first product, EyeArt, is for fully autonomous AI eye screening for detection of diabetic retinopathy. Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and has completed prospective clinical trials for an FDA clearance.

You will join a passionate team at Eyenuk comprised of software and machine learning experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (machine learning, computer vision, deep learning)

Would welcome anyone who wants to join our hands: have a young family? Great! Need a visa? We'll do everything legally possible to get you one.

jobs at eyenuk.com

Do they also sell their product with differential pricing in different markers? Does the product price also use a COL adjustment? If not, then why not? That does mean adjustments to salary based on location is not really a fair game.

This is insightful. The solution is probably to have a spot market for electricity that is accessible via an API so that smart AC or fridge or electric car charger can make use of it.

This will encourage market for devices that can utilize the lower spot prices dynamically and keep the things more efficient overall (in steady state).

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is an exciting medical software startup that has developed a powerful retinal image analysis AI platform for screening of diseases such as diabetic retinopathy and age-related macular degeneration.

Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and is under prospective clinical trials for an FDA approval.

You will join a passionate team at Eyenuk comprised of software and image analysis experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (image processing, computer vision, deep learning)

Would welcome anyone who wants to join our hands: have a young family? Great! Need a visa? We'll do everything legally possible to get you one.

jobs at eyenuk.com

I believe the self-service kiosks would be very much feasible. There are two key components: (1) automated non-mydriatic (not requiring dilation of the pupil) retinal imaging and (2) automated grading of images using AI.

The technology is there but there would be more work needed for a self-service kiosk to be FDA approved. Another thing that is not clear is whether it is commercially a good idea at this time, given that only a single disease (diabetic retinopathy) is approved. I can see a future where one can use such kiosks to look for multiple conditions and assess risks for various diseases including cardio-vascular disease, neurodegenerative diseases, stroke, and hypertension.

Thanks for this analysis. The balance in real world is more like 20-80, ie 20% of typically screened patients would have referable retinopathy (screen positive).

That's correct. UK is the only major (in some vague sense) Country where diabetic retinopathy is not the leading cause of preventable blindness in adults. This is very likely because they are able to screen more than 80% (nearing 85%) of their diabetic population, an impressive feat. This leads to another issue: they need to consistently grade the retinal images of over 2.2 million patients with diabetes. This is where AI could help -- in improving the consistency and turn-around time and we are working with the NHS UK to explore this.

This is not completely correct. Sensitivity (87% in this case) is not same as accuracy, nor is specificity (89.5% in this case) same as true negative rate.

Sensitivity generally gives an indication of safety of a medical device, and specificity gives a general indication of effectiveness.

As a founder of another company in this field, let me start by saying that this approval is a big deal. Kudos to IDx. This is the very first time FDA has approved a fully automated CADx (computer aided diagnosis) device. Eyenuk is also on it's way to an FDA approval and it is a lot of work conducting the prospective clinical trials.

There are some misconceptions on the thread, so let me help clear them up. A screening test is indicated on an annual basis for anyone with diabetes who does NOT have visual symptoms. Diabetic retinopathy (DR) progresses without any symptoms and is preventable if detected early, but despite its preventable nature, DR is the leading cause of blindness in working-age adults even in the developed world.

The test is for screening rather than providing a full diagnosis and is not intended to replace a dilated ophthalmologist examination. You don't need a specialist to screen, but you need a specialist to diagnose and treat. Sensitivity implies the percentage of times the test is able to correctly identify the presence of more than mild diabetic retinopathy (in this case, 87.4 percent of the time) and specificity is the percentage of times the test was able to correctly identify those patients who did not have more than mild diabetic retinopathy (in this case, 89.5 percent of the time). Note that neither sensitivity nor specificity implies accuracy. The sensitivity and specificity generally compare well to that achieved by humans.

Welcome to apply! Send an email to jobs at eyenuk dot com

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is an exciting medical software startup that has developed a powerful retinal image analysis AI platform for screening of diseases such as diabetic retinopathy and agre-related macular degeneration.

Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and is under prospective clinical trials for an FDA approval.

You will join a passionate team at Eyenuk comprised of software and image analysis experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (image processing, computer vision, deep learning)

Would welcome anyone who wants to join our hands: have a young family? Great! Need a visa? We'll do everything legally possible to get you one.

jobs at eyenuk.com

Eyenuk, Inc. | Software Engineers | Los Angeles, CA | ONSITE | VISA | Full-time |

Join us in building software platform to apply deep learning and robotics to help prevent blindness across the world. Eyenuk is an exciting medical software startup that has developed a powerful retinal image analysis AI platform for screening of diseases such as diabetic retinopathy and agre-related macular degeneration.

Anyone with diabetes is vulnerable to blindness that progresses without any pain or discomfort. Despite it's preventable nature, the condition, called diabetic retinopathy, is the leading cause of blindness in working age adults. Eyenuk has developed EyeArt, a SaaS offering, that automates the retinal disease screening process via automated analysis of retinal images and providing a screening referral outcome. EyeArt is a clinically validated on over 100,000 patients providing sensitivity that exceeds that of expert human graders. EyeArt has CE Marking (regulatory approval in Europe) and is under prospective clinical trials for an FDA approval.

You will join a passionate team at Eyenuk comprised of software and image analysis experts. We are hiring for multiple positions in the following two broad categories.

* Full-stack software engineers (Python, Frontend, UI)

* Algorithms engineer (image processing, computer vision, deep learning)

Would welcome anyone who wants to join our hands: have a young family? Great! Need a visa? We'll do everything legally possible to get you one.

jobs at eyenuk.com