jz_

HP acquired Palm for $1.2 billion in 2010, stumbled with a mobile product launch that was killed without much runway or developer investment: https://news.ycombinator.com/item?id=44270709 (article archived: https://www.thelayoff.com/t/1jxp06mns) - This no doubt soured people who cared about Palm.

HP were known for carrying Intel's Itanium business, for which few tech people have nostalgia for (the second hand market prices have always been eye-watering too), compared to the older PA-RISC line.

I'll agree their consumer/business laptops were always been perfectly usable and long lasting. I dumpster dived an excellent condition pentium 3 laptop from a HP Office that was probably thrown out because of a password locked BIOS (which was not resettable by battery removal, only by getting access to someone who had the bios password serial->keygen tool). It was a great daily driver with Debian, and wifi worked fine with ndiswrapper.

https://downloads.haskell.org/~ghc/9.4.2/docs/users_guide/co...

> -fvia-C

> Use the C code generator. Only supposed in unregisterised GHC builds.

> This is the oldest code generator in GHC and is generally not included any more having been deprecated around GHC 7.0. Select it with the -fvia-C flag.

> The C code generator is only supported when GHC is built in unregisterised mode, a mode where GHC produces “portable” C code as output to facilitate porting GHC itself to a new platform. This mode produces much slower code though so it’s unlikely your version of GHC was built this way. If it has then the native code generator probably won’t be available. You can check this information by calling ghc --info (see --info).

I'm using it right now. It is not particularly responsive (perform an operation and it looks like no operation is happening until the remote end responds) but works well enough for copying files in and out via nautilus if you don't expect instant feedback.

I seem to remember playing Commander Keen under DOSEMU seamlessly on a p200mmx with 64mb of ram. If this mail from 1999 is anything to go by, others were able to play similar vintage games:

https://web.archive.org/web/20000118171326/https://www.mail-...

https://blogs.sciencemag.org/pipeline/archives/2021/07/02/th...

What is meant by that though? Radio-labelling experiments do show that some dietary fat ends up as stored in fat cells.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2362....

https://en.wikipedia.org/wiki/Isotopic_labeling

A different study plans to evaluate Rapamycin for Alzheimer's disease, while being well aware of the positive effects on lifespan.

https://news.uthscsa.edu/ut-health-san-antonio-gains-2m-to-s...

I use an intel nuc i3-7100U as a wifi to ethernet bridge for a Windows 10 machine (HP Elitedesk 8300 Core i5-3470). The nuc also serves as a htpc running libreelec.

Why? I tried 4 different USB WiFi dongles with different chipsets spanning ~11 years and each one would end up being the cause of intermittent blue screen of death. The dump file backtrace repeatedly pointed to the usb-wifi stack.

* https://www.rejuvenatebio.com/ (Gene therapy for mitral valve disease in dogs)

* https://dogagingproject.org/ (Involved rapamycin which is already known to increase lifespan in model organisms)

* https://www.vaika.org/ Reverse transcriptase inhibitors in dogs to increase healthspan/lifespan.

> Personal use. You may use and play everything from the kunstderfuge.com web site and from its Services for your personal, non-commercial, use only. you agree not to reproduce, retransmit, distribute, disseminate, sell, broadcast, make available to third parties or circulate the musical content downloaded through the Service to anyone, or to exploit any such content for commercial or non-commercial purposes without the express prior written consent of kdf.

Might not necessarily be better, just different to satisfy the claim "BPA free".

> Methylglyoxal, a highly reactive dicarbonyl compound, is inevitably formed as a by-product of glycolysis. Methylglyoxal is a major cell-permeant precursor of advanced glycation end-products (AGEs), which are associated with several pathologies including diabetes, aging and neurodegenerative diseases. In normal situations, cells are protected against methylglyoxal toxicity by different mechanisms and in particular the glyoxalase system, which represents the most important pathway for the detoxification of methylglyoxal. While the neurotoxic effects of methylglyoxal and AGEs are well characterized, our understanding the glyoxalase system in the brain is more scattered

https://www.frontiersin.org/articles/10.3389/fnins.2015.0002...

I think he'd say living longer for remaining disease-free would just be a happy side-effect.

That said, there many companies working on aging biology now: http://agingbiotech.info/companies/

Can be used it to interact with the execution of the current program. It is simple as appending further code with a label and jumping to it using goto. I first noticed it in 2007 started using it in production.

If anyone is interested in a talk by one of the authors (Kevin Strange), he goes into the history of the compound here: https://www.youtube.com/watch?v=6aAr5pKW9Dw

For progress on similar lines of tech, this is a good site: https://www.lifespan.io/the-rejuvenation-roadmap/