jwco
It's-a-me, Mario and soon I'll be playing my games without your help …
Faysee makes it easy to get feedback from multiple people easily, or to see if you can make friends/family laugh.
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Joe Laws (hn: jlaws) built this app with me. Jon Collins (hn: jonathancollins) helped fix some bugs. Jordy Clements (hn: JordyClements) is the funny Snapchat-sending friend, wearing the crustacean hat in the linked video.
My Demo Video for Faysee, a Reaction Capture Messaging App
2D gaming using Processing.js
Show HN: My DIY-science attempt at the (literally) coolest ice bucket challenge
guns owned in America have mandatory geolocation installed. guns lock if geolocation is disabled or hacked, an alert is autosent to local people and authorities with the last known location, and law enforces speedy investigation of the guns whereabouts and reinstallation of the geolocator. i'd like an app that tells me where the nearest guns are to me and some info about who they belong to, i.e. police, citizen, military etc. if a gun is brought near public spaces, schools, theaters, etc., it should tweet, sms, or otherwise alert local police and anyone who would like to know. i'd like to also set my own alerts, such as alert me if a non-police gun is within a few hundred feet of my location, or my kid's location, etc. the constitution says there is a "right of the people to keep and bear arms," but does not use the word "right" to defend privacy.
That is interesting to me too though. I don't know why cells should stop dividing without telomeres, or with telomeres below a critical length. That suggests to me there is interaction with other cellular machinery at this onset of senescence.
I thought the idea was that telomeres are like chaff that the DNA drops over the course of many replication cycles instead of losing "more important" bases of DNA. In that sense telomeres might protect against loss of function (cancers). I did not know they prevented non-homologous end joining, but see how they could. I take it non-homologous end joining could lead to gain of function (cancers).
So what is the divide? Do some people think that telomeres protect cancer?
A comment above (http://news.ycombinator.com/item?id=4846137) suggests something like this. First a cell is converted into a cancerous state, perhaps even due to a lack of telomeres and subsequent loss or gain of function. Then telomerase somehow is upregulated. If there was some error correction process (to correct the loss or gain of function cancer), could the sudden increase in telomerase and telomere length prevent that error correction from occurring?
Combinatorial Creativity
Adopt a Hydrant
Should government be more like a computer game?
"Why shouldn't you do significant things in this one life, however you define significant? I'm not going to define it - you know what I mean. I will talk mainly about science because that is what I have studied. But so far as I know, and I've been told by others, much of what I say applies to many fields. Outstanding work is characterized very much the same way in most fields, but I will confine myself to science."
Bill of Rights on Rap Genius
Mark Zuckerberg's Favorite Rap Lyric on Rap Genius
Mark Zuckerberg's IPO Letter on Rap Genius
Former McDonald’s Honchos Take On Sustainable Cuisine
How Makerbots Replicator2 Will Launch an Era of Desktop Manufacturing
The Longevity of Rankings
Staggering Beauty
Full Color Images at 100,000 DPI Resolution, Using Metal-Laced Nano-Structures
If Kleiner Perkins practices sexism and/or sexual harassment, then they brought theses costs on themselves.
Forget the suit costing these things. The practice of sexism and sexual harassment by themselves costs "time, image, and distraction from its main work, finding value."