graboy
Re:New 3D thermal invisibility cloak makes objects disappear from infr...
on Sunday November 01, 2026 @06:35PM (#50331067)
Wow, a blanket!
Re:Anthropic S-1
on Monday October 26, 2026 @05:45PM (#50251478)
Even if these companies become the new American zaibatsus, that doesn't mean they aren't still operating underneath the US government and its laws and system, you don't magically escape that.
Re:Creatine uptake enhances antitumor immunity
on Thursday September 24, 2026 @03:40PM (#49835839)
That and everyone should be taking a statin.
Re:Claude Fable 5.1 and Claude Mythos 5.1
on Tuesday September 01, 2026 @05:25PM (#49528452)
You have a misunderstanding. Watermarking does not bias the responses in any way. How is this possible?
Before: "He leaped at the chance" - 33%. "Jumped at the opportunity" - 66%.
After: "He leaped at the chance" - 33%. "Jumped at the opportunity" - 66%.
But if you refresh your response from Anthropic 100 times:
Before: "Jumped at the opportunity" He leaped at the chance" "Jumped at the opportunity"
After: "He leaped at the chance" "He leaped at the chance" "He leaped at the chance"
The second one is detectable as being watermarked.
davmre has a good explanation that's more in-depth.
Re:Aristotle quotes on virtue, knowledge, and happiness
on Wednesday August 05, 2026 @05:52PM (#49189533)
These come from my own musings not someone else's - but bearing sycophancy in mind, I asked Claude and it told me this is basically the "strict church thesis" from sociology of religion, and linked me this paper, I think it lines up with my takes written from someone who has had this idea before: https://www.journals.uchicago.edu/doi/abs/10.1086/230409
Re:Aristotle quotes on virtue, knowledge, and happiness
on Wednesday August 05, 2026 @04:45PM (#49188754)
I've thought about this. Aristotle doesn't draw as hard of a line between right and wrong behavior or advocate for specific actions, with the right action depending on circumstance, and to finding the middle path. Traditional religions might be a bit more hardline, with specific rules or commandments. It's easier to identify with belonging to a particular group when the line between belonging and not belonging is more crisp and defined by particular practices.
Would love to know if others have takes.
Re:Aristotle quotes on virtue, knowledge, and happiness
on Wednesday August 05, 2026 @01:28PM (#49186057)
It's more social, the translation of political is coming from polis; man is by nature meant to be part of a city or community.
Re:Which streaming service was that on again
on Friday July 24, 2026 @09:42PM (#49043715)
I've advocated for this exactly. For alcohol it's called the three-tier system: https://en.wikipedia.org/wiki/Three-tier_system_%28alcohol_d...
Re:Scaling Laws, Carefully
on Saturday June 27, 2026 @03:11AM (#48695921)
Yeah I mean, if you and I were to play the word-guessing game where you needed to guess what next word I'm thinking of, there's always uncertainty in your guess because it's a game of partial information - you can't fully observe my inner state. But that doesn't mean you couldn't evolve a strategy that spends a really long time thinking and analyzing to get asymptotically close to the best guess. There's no limit on that intelligence.
Re:Three main saturated fats raise your cholesterol
on Friday April 03, 2026 @09:22PM (#47634591)
Re:Nihilistic Violent Extremism
on Thursday February 26, 2026 @09:51AM (#47166888)
Eric Hoffer would agree with this take.
Re:How often do full-body MRIs find cancer?
on Sunday February 15, 2026 @02:17AM (#47021691)
I kinda agree with you and I understand your point but I also think there is a social-ethical reality that if a doctor finds something they must treat it. The two options are 1. doing nothing, or 2. reducing cancer risk and you get unnecessary biopsies.
You're thinking of this as there being an objective positive utility for not dying of cancer and a objective negative utility for biopsies, and there being an objective optimal "rational" tradeoff that the best radiologist can optimize for to get their "nearly certain" detection threshold.
But frankly - the tradeoff for the value of a human life is perhaps the most uncertain thing one could choose. It lies in the eyes of the patient if the worry and time associated with a false detection is worth their reduced chance of death. The ethical uncertainty expressed in the OP - are these unnecessary biopsies worth it - is warranted.
Re:GPT‑5.3‑Codex‑Spark
on Friday February 13, 2026 @03:22AM (#47000305)
IIRC, a lot of design went into making it so that you can disable parts of this chip selectively.
Re:I Quit My Job at OpenAI
on Wednesday February 11, 2026 @02:29PM (#46979620)
If Anthropic's claim to never run ads is true, then won't users just switch over there?
Re:Can Ozempic Cure Addiction?
on Monday February 09, 2026 @09:48AM (#46945794)
N=1, I've been on GLP-1s for a long time and continue to be an obsessive.
Re:Cardiovascular disease is a solved problem
on Monday January 05, 2026 @05:12PM (#46505764)
> This is why the paper presented does not support the claim that LDL is the sole source of heart disease
Is that what we were arguing about? I guess it was. At some point in thinking about this my frame must have shifted into agreement with you. Of course there are other causes of heart disease besides LDL, like blood pressure, duh. The smooth dose response is about the particular gene not being linked to heart disease through something other than LDL, roughly.
Re:Cardiovascular disease is a solved problem
on Sunday January 04, 2026 @01:15PM (#46490595)
What do you think of Dr. Schooling's response that the Mendellian effects might be inflated? I think they had a good defense but was not entirely convinced they hadn't sidestepped the issue that Schooling was getting at, wasn't sure either way.
Re:Cardiovascular disease is a solved problem
on Sunday January 04, 2026 @12:41PM (#46490229)
I think maybe you are saying that there may be some way that the genes affect heart disease not through LDL, and therefore MR does not apply because the "exclusion restriction" [1] fails here? Or are you talking about a different assumption?
The cited study addresses this, which is why I pointed to figure 3. They argue that if genes were causing heart disease not through LDL in any meaningful way, you wouldn't expect such a clean dose-response consistency across different genetic variants - it would be more jagged.
[1] https://en.wikipedia.org/wiki/Mendelian_randomization#Defini...
Re:Cardiovascular disease is a solved problem
on Saturday January 03, 2026 @08:18PM (#46483753)
https://www.jacc.org/doi/10.1016/j.jacc.2012.09.017
Across different genetic variants, lower lifetime LDL -> lower risk of death. Check out figure 3.
The causality of LDL -> plaque buildup -> 55-60% [1] of heart disease related deaths is also well understood, so it seems clear to me that preventing plaque buildup in the first place prevents over half of heart disease related deaths.
Would like to know if you disagree, "Minimize LDL at all costs" goes current mainstream medical guidance, so I'd like to disconfirm my beliefs if possible.
[1] Number from deep research.
Re:Cardiovascular disease is a solved problem
on Saturday January 03, 2026 @04:03PM (#46481511)
Here is the chief editor of JAMA internal medicine arguing there is not enough evidence to prescribe statins for primary prevention in those 40+: https://www.natap.org/2016/HIV/ied160021.pdf
Re:Russia Creates New Military Branch Dedicated to Drone Warfare
on Saturday November 15, 2025 @02:19AM (#45935658)
what?
Re:Hydrogel-based expanding pill for weight loss shows promising resul...
on Tuesday October 21, 2025 @01:40AM (#45652817)
Gelesis100, another oral hydrogel, I understand is not very effective, I wonder what makes this one different?
Re:Empathy for Dummies
on Wednesday October 08, 2025 @09:51AM (#45516212)
To the extent empathy is "do onto others as others would do onto you", empathy has a moral justification derived from Kant's categorical imperative.
Re:Preventing Flash of Incomplete Markdown when streaming AI responses
on Thursday June 05, 2025 @08:39AM (#44191093)
Yes. You can define a regex matching what you want, and every regex can be compiled into a state machine (https://en.wikipedia.org/wiki/Nondeterministic_finite_automa...). Then at each character you make a step in your state machine. You pause the output while the regex is not matching.
Re:ChatGPT can now remember and reference all your previous chats
on Friday April 11, 2025 @01:24AM (#43650747)
I wonder how this works? Are they just RAG-ing the chat history or something more clever?
Re:US court upholds Theranos founder Elizabeth Holmes's conviction
on Tuesday February 25, 2025 @09:32AM (#43172331)
She is a psychopath, she has not changed, the "loving, caring mother" thing is a false persona she has created.
Re:What the Most Famous Book About Trauma Gets Wrong
on Friday January 17, 2025 @09:17PM (#42745217)
Bad article. Straw-manning and borderline lying about the book.
Re:NYC Announces 'Drone as First Responder' Program to Reduce Response...
on Tuesday November 19, 2024 @03:02PM (#42187492)
Seems timely for Half-life 2's 20th birthday.
Re:Can humans say the largest prime number before we find the next one?
on Friday November 08, 2024 @10:35PM (#42092363)
No.