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garysieling

Re:Ask HN: Who is hiring? (November 2026) on Monday November 02, 2026 @08:56PM (#50347008)
Certara | Sr. DevOps Engineer | REMOTE (US, Budapest) | Full Time

Certara makes software that life sciences companies use to develop drugs and get them approved. Our products model how drugs behave in the body (biosimulation) and validate clinical trial data for submission to regulators like the FDA.

We’re hiring a DevOps engineer to help grow the infrastructure behind our cloud products. You’ll work on:

CI/CD pipelines: CircleCI, Jenkins Cloud infra: AWS, Terraform, Chef Security/compliance: ISO 27001, GxP validation

US Listing: https://careers.certara.com/jobs/2614/job

Hungary: https://careers.certara.com/jobs/2492/job

We also have several engineering and product management roles.

Certara - We have software products for accelerating the development of medicines.

https://www.certara.com/certara-careers/

https://www.certara.com/company/our-story/

Re:Ask HN: Who is hiring? (April 2022) on Saturday April 09, 2022 @08:06AM (#30967314)
Pinnacle 21 - Software & UX engineers - REMOTE Based in the Philadelphia area, Pinnacle 21 is a leader in clinical trial data software and services. Our vision is a clean data pipeline that ends in a successful regulatory submission. Come help us revolutionize clinical trials and streamline the drug approval process.

View jobs here: https://technical.ly/company/pinnacle-21/

Here are articles about a couple members of our team:

https://technical.ly/professional-development/pinnacle-21-so...

https://technical.ly/company-culture/pinnacle-21-hiring-saas...

Re:Ask HN: Who is hiring? (March 2022) on Tuesday March 01, 2022 @02:03PM (#30518492)
Pinnacle 21 - Software & UX engineers - REMOTE

Based in the Philadelphia area, Pinnacle 21 is a leader in clinical trial data software and services. Our vision is a clean data pipeline that ends in a successful regulatory submission. Come help us revolutionize clinical trials and streamline the drug approval process.

View jobs here: https://technical.ly/company/pinnacle-21/

Here are articles about a couple members of our team:

https://technical.ly/professional-development/pinnacle-21-so...

https://technical.ly/company-culture/pinnacle-21-hiring-saas...

Re:Zine machine: a compact 3D-printed block printing press on Friday February 26, 2021 @11:02AM (#26276124)
Wood is pretty common for type, especially poster sizes, and there are some hobbyists still who use it for engravings
Re:Zine machine: a compact 3D-printed block printing press on Friday February 26, 2021 @10:51AM (#26275990)
You can get cool textures with alternative printing techniques. The inks used in printmaking are also very pigmented, so you get very rich colors/blacks, as well as some pigments you wouldn't get in a typewriter (e.g. dayglo colors)
Re:Ask HN: What did you make during lockdown? on Sunday June 21, 2020 @01:40PM (#23593662)
Yeah, it's really satisfying, even for quick experiments
Re:Ask HN: What did you make during lockdown? on Sunday June 21, 2020 @12:13PM (#23592859)
I've been doing woodblock printmaking - https://www.instagram.com/garyprints/
Re:Ask HN: What projects are you working on now? on Saturday March 21, 2020 @04:56PM (#22650001)
DevOps work for the Penn CHIME project (hospital capacity planning tool)

https://predictivehealthcare.pennmedicine.org/2020/03/14/acc...

Do you intend to have built-in support for user management?

Setting up stuff like Oauth / Okta / etc and handling things like who can access admin screens seems to consume a lot of time on new projects - it'd make for an awesome app platform if some of that was well-supported out of the box.

Re:Ask HN: Who is hiring? (March 2020) on Tuesday March 03, 2020 @06:59AM (#22473678)
US
Re:Ask HN: Who is hiring? (March 2020) on Monday March 02, 2020 @08:39PM (#22471052)
Element 84 | Alexandria, VA | REMOTE or Local | Senior DevOps Engineer

Senior DevOps / Cloud Engineer (Remote Friendly!) to help us build large scale data pipelines with remote sensing and life sciences data in the cloud.

Job Description + Apply here: https://jobs.smartrecruiters.com/Element84Inc/74399970673121...

Apply above, I'm not the hiring manager available if you have questions - gary @ company name . com.

Re:Ask HN: What Skills to Acquire in 2020? on Tuesday February 04, 2020 @06:53PM (#22242482)
AWS
Re:Amazon Kendra: Enterprise Search Service on Tuesday December 03, 2019 @02:28PM (#21695748)
From the demo it looked like an alternate way to search things like corporate portals. I.e. they're trying to improve the search that products like SharePoint provide with some ML integration.
Re:Ask HN: Are Lucene/Solr/ES Still Used for Search? on Friday July 19, 2019 @08:51AM (#20478194)
I'm using Solr for https://www.findlectures.com, but I think Vespa looks interesting - lets you store feature vectors in the index, so you can do neat things to incorporate ML algorithms in ranking.
Re:Ask HN: Who is hiring? (June 2019) on Monday June 03, 2019 @03:03PM (#20086942)
Element 84 | Software & DevOps Engineers | Alexandria| Full-time, REMOTE

https://www.element84.com/careers

We're taking on some of the biggest challenges in software: petabyte search, consumer streaming, and Earth science repositories, just to name a few. We are a team of gamers, musicians, artists, pitmasters, pilots, and tinkerers and we think you might have fun helping us solve some big problems.

Element 84 was founded by husband-and-wife engineers and has grown into a skilled group of developers, designers, project managers, and business team that build high performance systems for some of the biggest corporate and government clients in the world. Our main office is located in Alexandria, VA but we support a large remote workforce from Michigan to Texas and Pennsylvania to Colorado.

If you have questions, email me at [email protected] and I'll get reply quickly.

This is also a great way to become a better engineer - a lot of jobs are improving existing systems, so you get a different category of lessons building something from scratch to completion. Doing a write-up at the end is also teaches you to communicate better.
Re:Ask HN: How to incorporate machine learning into day job? on Monday December 10, 2018 @03:34PM (#18650980)
If you explore the word2vec family of algorithms, you can improve text search by pulling in external datasets. E.g. use a model trained on Wikipedia to find synonyms, or build a neural network that maps user search terms to documents in your database.
Re:Ask HN: How do you manage UI/UX for your side projects? on Friday December 07, 2018 @10:32AM (#18628459)
I use a framework - I like Semantic UI a lot, although I'm not sure it's being maintained. When selecting a framework, I like to resize the browser to see how responsive it is, and look for text overlap defects at different sizes as a sign of library quality.

Adobe XD is also a free prototyping tool - I would go through a tutorial or watch a few youtube videos of people working to get a feel for it.

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