Ask HN: What company environment has enabled your best work?
Interested in specifics around team dynamics, communication, learning, decision making, physical layout, etc.
g10r
Re:Ginkgo Bioworks (YC S14) is going public today
on Friday September 17, 2021 @08:18PM (#28572336)
yep! have def had one drop after conversion.
Re:Ginkgo Bioworks (YC S14) is going public today
on Friday September 17, 2021 @04:00PM (#28570263)
It's not bad per se, it's just how it works. Like pretty much everything in life the outcome is dependent on the people involved. You're not getting the potential for more upside without the introduction of more risk.
Chamath is currently leading four biotech SPACS: DNAA, DNAB, DNAC and DNAD, each with a stated target, neurology, oncology, organs & immunology. Anyone looking to invest in the SPAC today should consider the likelihood of this happening, the potential targets, and the sponsors history.
Or you can wait for an announcement around a proposed merger, even up to the day the official stock starts being traded.
Again, just depends on risk tolerance. It's nice to least have the option to take part in these deals.
Re:Ginkgo Bioworks (YC S14) is going public today
on Friday September 17, 2021 @03:24PM (#28569885)
Probably not...I just came across it as part of my diligence before investing. Originally found on Twitter.
Re:Ginkgo Bioworks (YC S14) is going public today
on Friday September 17, 2021 @03:23PM (#28569868)
Was nice to have the ability to buy into SRNG early. This is more or less restricted to most through a traditional IPO.
Re:Ginkgo Bioworks (YC S14) is going public today
on Friday September 17, 2021 @03:11PM (#28569712)
Here's one of their more recent decks if anyone is interested:
https://www.ginkgobioworks.com/wp-content/uploads/2021/08/20...
Re:Building AI Trading Systems
on Friday June 26, 2020 @08:15PM (#23658429)
Agreed. Many smaller, yet successful Hedge Funds limit the capital they manage for this very reason. Some strategies just don't work at certain scale.
Re:Ask HN: Engineering group to fight Covid-19 needs fee waiver from S...
on Thursday March 12, 2020 @07:10PM (#22563014)
Did they adjust based on this HN post?
We are wanting to get the My Climate Journey Slack account (550+ people) upgraded as well...
Re:SEC proposes changes to “accredited investor” definition
on Monday February 17, 2020 @11:54PM (#22353554)
For the most part, the government shouldn't get to tell people what they can or can not do with their money. We don't currently stop people from going to vegas, buying lotto tickets, buying expensive cars, clothes, buying education, etc.
Said another way, 'anyone' can invest 'any' amount in a public stock today and lose it all tomorrow. Heck people were even suckered into mortgages they couldn't afford by our trusty banks.
Re:Tesla to raise prices and keep more stores open
on Monday March 11, 2019 @03:09PM (#19361838)
Tesla occupancy doesn't mean much for most of these malls/shopping centers, to be honest.
Apple/Nike/Target, sure. Tesla, no.
Re:Tesla to raise prices and keep more stores open
on Monday March 11, 2019 @02:51PM (#19361687)
Surely they understood this before the initial decision was announced. No way those leases were disappearing.
Re:Ask HN: What company environment has enabled your best work?
on Friday February 08, 2019 @10:25PM (#19120496)
Funny enough I've been obsessing over this concept of "aligning vectors" / measuring the impact of personal KPIs against the total progress of a business.
“Every person in your company is a vector. Your progress is determined by the sum of all vectors.” — Elon Musk
Re:Gum disease–causing bacteria could spur Alzheimer’s
on Friday January 25, 2019 @12:40AM (#18995843)
Certainly important for people to understand/be aware of the process someone such as Robert Moir (one scientist mentioned in the article) must navigate
https://www.statnews.com/2018/10/29/alzheimers-research-outs...
Re:Gum disease–causing bacteria could spur Alzheimer’s
on Friday January 25, 2019 @12:39AM (#18995840)
Awesome thank you.
Re:Brain researchers warn that lack of sleep is a public health crisis
on Friday January 25, 2019 @12:12AM (#18995732)
Sleep is fascinating to study. So much to discover.
Awesome book: Why We Sleep by Matthew Walker
Re:Ask HN: How to pitch startup to corporates without losing ownership?
on Wednesday January 16, 2019 @09:16PM (#18927716)
The best protection is going to be execution.
NDAs aren't really going to help you in this regard.
Just take some meetings, tell them what you're working on and if some form of collaboration is of interest.
Re:Ask HN: Does ML research ever get translated to industry?
on Tuesday January 08, 2019 @05:42PM (#18860504)
What are you working on?
Re:Ask HN: Advice on acquiring clients for private beta?
on Tuesday January 08, 2019 @03:17PM (#18859243)
Approaching as a "partnership" may be useful. You can always increase pricing after your initial customers.
Also, be careful thinking you have a solid MVP.
Re:Ask HN: How to found a company as a single founder?
on Tuesday January 08, 2019 @03:10PM (#18859176)
arbitrary number + that's what, a couple months? That's nothing.
Re:Ask HN: How to found a company as a single founder?
on Tuesday January 08, 2019 @03:07PM (#18859142)
options:
1. start over and don't work with the current cofounder.
2. keep going with current product, structure co-founders financial contribution as an investment (use a SAFE or something) and remove the person from day to day operations in the company.
Re:Amazon Starts Selling Software to Mine Patient Health Records
on Tuesday November 27, 2018 @10:28PM (#18549075)
Re:AI Playbook
on Friday November 16, 2018 @04:19PM (#18472054)
There's a long-standing relationship there.
Re:AI Playbook
on Friday November 16, 2018 @03:59PM (#18471909)
Well, one reason to "keep up with trends" is because if your direct competitor does use ML to unveil some market/product/business opportunity or optimization, and you (executive/CIO/CEO) weren't at the least looking into the technology, heads are going to roll.
Re:AI Playbook
on Friday November 16, 2018 @03:55PM (#18471887)
Yes, similar to what CAA did for the entertainment agency world. You may find it interesting to read, Who is Michael Ovitz?
Re:Facebook is taking on Tinder with new dating features
on Tuesday May 01, 2018 @08:00PM (#16972896)
Soon people will receive the following message from FB: “Hey, meet/date/marry this person. Trust us, you are perfect for each other." :)
Re:Poor Grades Tied to Class Times That Don’t Match Our Biological Clocks
on Friday March 30, 2018 @05:41PM (#16720019)
100%
Re:Snap is laying off about 100 engineers
on Wednesday March 07, 2018 @05:08PM (#16540411)
Reducing engineering capacity does not necessarily mean reducing the pace of a companies innovation.
Re:The Business of SaaS
on Tuesday February 20, 2018 @10:38PM (#16426647)
Connections certainly help but aren't required. You need grit and a solution (or an idea of a solution) that's solving a pain point worth paying to alleviate. Ideally 10x better and cheaper than what's currently in the market. At first, you will be the salesperson and you have to realize that comes with a lot of rejection.
Re:What makes truly great leaders, the compression of seed and the fut...
on Wednesday January 17, 2018 @07:39PM (#16173571)
- conviction around ideas that are right, but not consensus. Rebel thinking.
- update your mental model with data.
- conversations around what's working, not working.
- one thing about a founder to decide to invest: shadow a founder for a day. Real life better demonstrates true nature of people vs meetings/stories/emails/interviews.
- always think about what can go wrong with your product, strategy, competitive landscape. Extreme alertness.
- if you have a good product, you can fix sales, customer success, marketing, etc. If you have a bad product, even doing everything else write doesn't help.
- Concerned about excess capital in seed markets. Bad companies shouldn't be raising money. Bad for the ecosystem as a whole.