emiller88
Rewrites.bio: 60x speedup in Genomics QC and AI rewrite principles for Science
Re:Rewrites.bio: 60x speedup in Genomics QC and AI rewrite principles ...
on Thursday April 02, 2026 @12:25PM (#47616596)
AI coding assistants have made it possible for domain experts to rewrite established scientific software in days. We believe that a wave of AI-driven tool rewrites is coming to bioinformatics. We've published a set of best-practices principles to help people to approach rewrites in the right way. Along the way we fully rewrote and open-sourced the genomics QC tools for RNAseq, the most widely used genomics pipeline, yielding a >60x performance improvement.
Re:Uv's killer feature is pulling in local dependencies
on Sunday January 12, 2025 @04:06PM (#42676941)
There's so many more!
1. `uvx --from git+https://github.com/httpie/cli httpie` 2. https://simonwillison.net/2024/Aug/21/usrbinenv-uv-run/ uv in a shebang
Migration from Biocontainers to Seqera Containers: Part 1
Setting Up Doom Emacs for Astro Development
Using Age with Org-Journal
The Good Research Code Handbook
Re:Firefly III: A free and open-source finance manager
on Monday May 30, 2022 @05:55PM (#31564044)
Agreed. I've found https://lunchmoney.app/ really nice.
Re:The new and upgraded Framework Laptop
on Thursday May 19, 2022 @01:51PM (#31437892)
FYI, we've added support for the framework to nixos-hardware. I appreciate any feedback or improvements anyone has!
https://github.com/NixOS/nixos-hardware/blob/master/framewor...
Re:NixOS on Framework Laptop
on Monday October 18, 2021 @10:24PM (#28914210)
https://github.com/NixOS/nixos-hardware/issues/323
Created an issue for this for anyone interested!
Re:Ask HN: Best way to learn computational biology/immunology?
on Saturday January 16, 2021 @12:50PM (#25803858)
The resource I recommend to people looking to move from wet lab to dry lab stuff is https://www.biostarhandbook.com/. From your post history it looks like you already have some programming experience, so you could skip the first few chapters which are just a linux intro. I don't think it has all the best practices, but I think it's the most comprehensive overview that starts from square 1 and fills in all the gaps no one tells you when you first start, for example the "Common data types" chapter.
Re:Ask HN: Where do you find new music to listen to online?
on Saturday August 17, 2019 @02:05PM (#20725349)
My friend has been working on a personal project to do just that! Check it out! Plug - https://plug.af/
New $stdout – My Language
Re:Choose Firefox Now, or Later You Won't Get a Choice (2014)
on Friday December 07, 2018 @11:03AM (#18628740)
Anyone have any thoughts on Firefox vs Brave?