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Single Neuron Changes Can Steer LLM Behavior in Surprising Ways
Poisoned Open Weights
Vector2Variant: Discovery of Genetic Associations Without Phenotype Engineering
Trait Causal Models: GWAS, perturbations to predictive models of human biology
Cellular scaling laws in the mammalian brain
https://unsloth.ai/docs/new/studio#unsloth-as-an-api-endpoin...
Llama.app/.cpp and Unsloth Studio on Mac already provide guidance to pick the optimal model for the available memory, all model wheights hosted by huggingface. Both apps can use the local huggingface model cache locally.
If you make it configurable, the user could also run a separate machine with an NVidia card and Linux to serve tokens on the LAN. Or use OpenRouter or any other cloud hosted model offering (DeepSeek, Z.ai, etc.).
DocCloak – Browser-Based Document Anonymizer for AI Submissions
Don't Feed the AI - Anonymizer Proxy for AI-assisted Pentesting
One concern I have is about sending private info to Anthropic. So it would be great to have the option to use local AI.
Local options should support the OpenAI API that seemingly is the standard for these connections, as provided by Llama.app and Unsloth Studio for example. That way one could run against a local model and keep personal information private.
That of course begs the question if a local model is smart enough for the tasks at hand.
I'm also trying out OOMU, a similar but closed source personal assistant app for MacOS. It emphasizes privacy with local models, and even has an 'Airplane' mode. The app has a built in llama.cpp server and uses Gemma-4-4B, their own router model plus a vision model.
Crazy how my gut feeling was more than vindicated.
In Depth Stanford Student Newspaper Article about Noble Winner Karl Deisseroth
EUV Photomasks Are Getting Bigger [video]
Model with metacognitive guidance identifies zero-click full-chain RCE in BlueZ
I do like the sound of Verscheissification.
As Picard said: Enshitify! (Apologies to my Trekkie friends.)
You can chat with any model in the built-in WebUI, connect other apps (coding agents, chat UIs, editors), or use the API directly. Models load when requested and unload when idle, so they don't take up memory when not in use.
> Features
- 100% local — Models run on your Mac; no data ever leaves it
- Small footprint — 4 MB native macOS app
- Zero configuration — models are auto-configured with optimal settings for your Mac
- Model recommendations — a built-in list of models your Mac can run, installable in one click
- Standard storage — models live in the Hugging Face cache, shared with llama.cpp and other tools
- Built on llama.cpp — from the GGML org, developed alongside llama.cpp
> Installation
To install llama.cpp , run:
brew install llama.cpp
To install llama-app, run: brew install --cask llama-app