alfon
Re:15-minute at-home Lyme disease tick test
on Saturday June 20, 2026 @11:10PM (#48615328)
You're the smart one.. Unfortunately I didn't find the tick on time and have been sick with persistent Lyme for over 10 years. Hoping for some kind of solution soon.
Re:Palantir and other tech companies are stocking offices with tobacco...
on Thursday March 05, 2026 @10:46AM (#47262993)
Not much different than a fully stocked fridge with alcoholic beverages.
Consume responsibly, we're all adults.
Re:Slop Detective – Fight the Slop Syndicate
on Wednesday November 26, 2025 @03:58PM (#46062239)
But then it wouldn't classify as slop?
Re:12ft.io Taken Down
on Monday July 21, 2025 @03:43PM (#44639562)
Re:A Single Div
on Friday May 03, 2024 @03:40AM (#40245203)
The "about" page is a comment in the HTML source:
> This is a CSS drawing experiment to see what's possible with a single div. To learn more about this project: GitHub: https://github.com/lynnandtonic/a-single-div Mozilla Hacks: https://hacks.mozilla.org/2014/09/single-div-drawings-with-c... Talk from CSSDay: https://lynnandtonic.com/thoughts/entries/talk-illustration-... Codepen: https://codepen.io/lynnandtonic Mastodon: @[email protected] Twitter: @lynnandtonic
Re:Adult Attention-Deficit/Hyperactivity Disorder and the Risk of Deme...
on Tuesday October 17, 2023 @07:47PM (#37923072)
I have a brain disease driven by an infection that gets better with long term antibiotics.
One of my main symptoms was MCI. Interesting that after long term treatment not only the MCI improved or subsided but also my very long standing ADHD (present for as long as I can remember) got dramatically better, makes you wonder.
Re:The Secret Weapon Hackers Can Use to Dox Nearly Anyone in America f...
on Tuesday August 22, 2023 @03:15PM (#37227313)
Would a credit freeze prevent data brokers also accessing the credit header?
Re:Ask HN: I'm 40 and feel my mental ability declining. Programming se...
on Tuesday January 10, 2023 @12:56PM (#34328739)
For someone who has been forced to try countless substances / diet regimens / health strategies due to a pervasive chronic disease, I beg to differ. There's so many things that you can personally do that will alter your cognitive abilities, sometimes to an incredible extent. The tricky bit is that there is indeed no silver bullet, and what works for someone might do nothing or create harm for another. So in my opinion, understanding that there are alternatives to resignation is really the critical component.
Re:Vitamin D supplementation worsens Alzheimer's progression
on Monday July 25, 2022 @02:37PM (#32228952)
Try assessing your Plasmalogen levels.
https://prodrome.com/blood-test/
Hearing very interesting (yet unpublished) results coming out of Dayan Goodenowe's trials of supplementing Plasmalogen precursors on Alzheimer patients. A lot of folks over at APoE4.info have been on the precursors for many months.
Re:Killbutmakeitlooklikeanaccident.sh
on Sunday July 17, 2022 @10:14AM (#32126942)
Seems it wasn’t just “possession of an oil filter silencer”:
> Candelario sold and manufactured AR-15 style assault rifles in Maryland without a license. The ATF caught Candelario by using an anonymous man to purchase the firearms in a gas station parking lot. This agent purchased six rifles, as well as two fuel filter silencers.
Re:Missing link between Alzheimer’s and vascular disease found?
on Friday May 27, 2022 @02:11PM (#31532813)
With respect to Dayan Goodenowe and his Plasmalogen theory, I think the Rush study should be reproduced by other groups. I am no qualified to judge it either, but thinking critically, unless some glaring statistical mistakes were made, or error measuring the levels, or simply that plasmalogen deficiency is a biomarker more than causative (he goes at length as to why he considers it to be the latter), we are talking about natural compounds (Plasmalogen precursors, or IV plasmalogens) that do not require FDA approval, so it should be fairly straightforward to fund, develop and test.
“The clinical implications of this study are obvious. This is the first reported evidence of a metabolic phenotype with the same clinical characteristics as the APOE ε2ε3 genotype. The probability of dementia in participants with either a high PBV or an APOE ε2ε3 genotype was indistinguishable”
Re:Missing link between Alzheimer’s and vascular disease found?
on Thursday May 26, 2022 @09:00PM (#31525035)
I recommend to take a look at this interview by the very Bredesen, to a scientist called Dayan Goodenowe, working also on the Alzheimer problem. He has a very interesting book called "Breaking Alzheimer" that postulates that DHA Plasmalogen deficiency is causative for Alzheimer. Very interesting stuff:
https://www.apollohealthco.com/facebook-live-plasmalogens-an...
Re:An ALS Protein, Revealed
on Sunday March 13, 2022 @06:26PM (#30666357)
Was reading this article and this comment came to my mind.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4832962/
"Organophosphate poisoning is highly lethal as organophosphates, which are commonly found in insecticides and nerve agents, cause irreversible phosphorylation and inactivation of acetylcholinesterase (AChE), leading to neuromuscular disorders via accumulation of acetylcholine in the body."
Re:An ALS Protein, Revealed
on Sunday March 13, 2022 @06:24PM (#30666344)
Depends on the antibiotic. I believe their molecular mass has to be lower than around 500 Da for them to reliably cross the blood brain barrier. It also depend whether meningeal inflammation is present or not
Re:An ALS Protein, Revealed
on Friday March 04, 2022 @05:48PM (#30561670)
"Ticks love to be in moist, low grass, so a lot of games, whether it's football, baseball, tend to happen in the morning. There may be dew on the grass and that's where a lot of ticks survive and hang out," Nesheiwat said.
https://www.cbsnews.com/newyork/news/ticks-lyme-disease-cdc-...
Lots of anecdotal evidence of ALS developing after tick bites, or more concretely infection with Borrelia Burgdorferi.
Probably a genetic component, and other enviromental factors are also involved, but the only dramatic reversals of MND I have seen documented (or heard about) have been either with IV antibiotics [1][3], or years of Mercury chelation [2]
[1] https://invisibledisabilities.org/award-recipients/2011award...
[3] https://pubmed.ncbi.nlm.nih.gov/17212618/
[2] https://www.researchgate.net/publication/317849075_Healing_o...
In the recent book "Chronic" by Dr. Stephen Philips, he's frustrated since he can only treat successfully (outcome similar to Dr. Martz), with antibiotics, about 15% of his ALS-like patients. Considering how uniformly fatal ALS diagnosis is otherwise, even considering how skewed of a sample he might get (patients that already know they are Lyme positive or suspect it), still find it astonishing.
Re:An ALS Protein, Revealed
on Friday March 04, 2022 @05:28PM (#30561467)
Re:Show HN: Looptap – A minimal game to waste your time
on Thursday January 13, 2022 @03:36PM (#29926469)
Thanks for the note!
Re:Show HN: Looptap – A minimal game to waste your time
on Thursday January 13, 2022 @12:21PM (#29923562)
You beat me to it, haha, This is what I just did:
function intersectRect(rectA, rectB) { return !( rectB.left >= rectA.right || rectB.right <= rectA.left || rectB.top >= rectA.bottom || rectB.bottom <= rectA.top ); }
const arc = document.getElementById("arc"); const ball = document.getElementById("ball");
setInterval(() => { if (intersectRect(arc.getBoundingClientRect(), ball.getBoundingClientRect())) { window.dispatchEvent(new KeyboardEvent('keypress', { keyCode: 32, })); } }, 10);
My code seems to go on forever, closed the tab after it reached 60K
China finally discovers the truth behind the moon's “Mystery Hut”
Re:Lab Leak 2.0?
on Thursday January 06, 2022 @07:16PM (#29832733)
Note that the author does not imply that Delta originated from a lab, but rather that Delta leaked from a lab at the end of 2021, and cites a supporting source.
Dr. Dayan Goodenowe: Plasmalogens and Alzheimer's
Re:Drug treatment for Lyme disease could lead to its eradication
on Tuesday October 12, 2021 @11:16AM (#28840754)
My question would be how easy is for this molecule to cross the blood brain barrier. Perhaps if toxicity is very low you can diffuse it somewhat by maintaining high levels in blood, but my understanding is that molecules with a weight of more than 400daltons have trouble crossing it.
It might be also true that a certain percentage of lyme patients have some level of meningeal inflammation that might facilitate crossing more.
Drug treatment for Lyme disease could lead to its eradication
Re:A shot to prevent Lyme disease could be on its way
on Tuesday August 17, 2021 @01:09PM (#28212232)
Thanks for that link, super interesting.
Check out also Dualdur, received 3MEur from EU in 2018.
Re:A shot to prevent Lyme disease could be on its way
on Tuesday August 17, 2021 @12:59PM (#28212112)
Any reason why this injection of OspA Monoclonal Antibodies wouldn't help in late disseminated Lyme disease?.
My understanding is that very tough cases of neurological Lyme disease often benefit greatly from IVIG. Wouldn't this be a more targeted version of IVIG?
Lessons Learned Replicating a PostgreSQL Cluster to Redshift with AWS DMS
Re:Alzheimer’s enigma: Why is incidence falling 16% a decade in riches...
on Friday July 02, 2021 @12:31AM (#27707830)
Indeed, every measure that helps decreasing the overall heavy metal burden is welcomed.
One of such is the Minamata convention on Mercury [1].
"Studies also confirmed that neurotoxic metals, including lead, mercury, aluminum, and manganese, are measurably more harmful in combination than separately" [2]
One researcher that has been advocating for the link between mercury toxicity and Alzheimer's is Dr. Boyd Haley [3].
Lastly, here is a cool video showing how Mercury causes neuron degeneration: https://www.youtube.com/watch?v=bpC17nfZVvU
[1] https://en.wikipedia.org/wiki/Minamata_Convention_on_Mercury
[2] DOI:10.1588/medver.2005.02.00070 [3] https://www.youtube.com/watch?v=8AQxkIcXrt0 [4]
Re:Complexities of e-mail validation logic
on Monday May 24, 2021 @11:42AM (#27265669)
Or use a password manager.
Re:Select a muscle and it provides the exercises to workout the select...
on Thursday January 21, 2021 @01:38AM (#25856177)
I hear you on this problem. You might consider checking out the articles and videos from https://mskneurology.com/. It's a superb resource.