Utkarsh_Mood
Re:FDA clears blood test to aid evaluation for Alzheimer's disease
on Wednesday August 26, 2026 @03:45PM (#49454760)
While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to be hard to model with AlphaFold. I work on computational modeling, so if I had to guess, I'm very unsure if people are using it for whole protein modeling, rather than looking at more specific domains where it probably does much better.
Re:I believe there are entire companies right now under AI psychosis
on Friday May 15, 2026 @05:42PM (#48154290)
share the prompt!
Re:Ask HN: Could you share your personal website here?
on Wednesday January 14, 2026 @12:59PM (#46619570)
Re:Show HN: Cancer diagnosis makes for an interesting RL environment f...
on Wednesday November 12, 2025 @05:15PM (#45907580)
fair enough. I wonder if fine-tuning over different modalities like IMC, H&E etc would help it generalize better across all
Re:Show HN: Cancer diagnosis makes for an interesting RL environment f...
on Wednesday November 12, 2025 @03:36PM (#45906259)
none of the models you mentioned are open source...
Re:Show HN: Cancer diagnosis makes for an interesting RL environment f...
on Wednesday November 12, 2025 @03:32PM (#45906169)
Do you think finetuning these LLMS would bring about comparable results to specific models trained for this?
Ask HN: Advice you'd give to your 18 year old self?
Just turned 18 today. Any personal or professional advice you wished someone gave you when you were 18?
Re:YC: Requests for Startups
on Thursday February 15, 2024 @11:04AM (#39384360)
going of a tangent but would you say it's worth going to a similarly ranked uni(oxford) if one wants to go into entrepreneurship given its more 'academic' emphasis? as opposed to somewhere like UCSD where it's not as prestigious but close to the tech scene.(bonus points for california weather ha!)
Re:YC: Requests for Startups
on Thursday February 15, 2024 @10:58AM (#39384277)
sad to see no neuro-ai , is it too early?
Re:Ask HN: What are your predictions for 2024?
on Thursday December 28, 2023 @05:04AM (#38791880)
maybe its naïvety, but I expected a more optimistic/positive outlook from the hacker community lol.
Re:Ask HN: What are your predictions for 2024?
on Wednesday December 27, 2023 @06:58AM (#38781152)
just curious, why are so many predictions so pessimistic?
Re:Tell HN: Merry Christmas
on Monday December 25, 2023 @12:12PM (#38764253)
Praying next year is better for you and your family
Re:Tell HN: Merry Christmas
on Sunday December 24, 2023 @10:21PM (#38759372)
Merry christmas HN!
Re:Ask HN: What is your most wanted HN feature?
on Wednesday December 20, 2023 @10:41PM (#38716755)
a direct messaging system, there've been countless times when I've wanted to ask a poster some (unrelated) questions, but they have no contact details.
Happy Diwali HN
Just wanted to wish everyone a happy Diwali
Fine-tuning GPT3.5-turbo based on 140k Slack messages
Re:Ask HN: Did any of you first encounter programming through Scratch?
on Thursday October 19, 2023 @07:18AM (#37941260)
yeah scratch, visual basic and swift playgrounds got me into it. Great for piquing interest, especially being able to see projects others built and interact with them.
Re:Show HN: I built an app that lets you create and chat with 3D AI ch...
on Friday September 15, 2023 @07:59AM (#37521681)
super cool! what model are you using for this?
Ask HN: Resources to Get Started with Neurotech
Any resources you'd reccomend to a beginner?
Re:Become an expert in something specific and boring
on Monday September 04, 2023 @11:39PM (#37387588)
Sam isnt really a proponent of EA, for what its worth.
Ask HN: Resources to Get Started with Neurotech
Hi HN,what are some good resources you'd reccomend to someone who's hoping to get their feet dirty in the neuroscience/ai field? Have found relatively few materials/courses/books out there.
Re:Ask HN: Great resources for university calculus/physics?
on Friday August 25, 2023 @01:47PM (#37264752)
*in thinking
Re:Ask HN: Great resources for university calculus/physics?
on Thursday August 24, 2023 @11:10PM (#37257545)
Would add "Aptitude Test Problems in Physics",S. S.Krotov. It is tougher than Irodov but definitely improves upon your skill in think about hard problems
Re:Launch HN: Rubbrband (YC W23) – Deformity detection for AI-generate...
on Thursday August 10, 2023 @12:57PM (#37078663)
iirc midjourney has figured it out although its closed source if you were wondering.
Re:Show HN: An app to help you stay Focused
on Saturday July 29, 2023 @04:24AM (#36918125)
Looks great! If you could make this a PWA i'd download it for sure.
Suggestion: If you could set intervals of deep work for around 1.5 hour's too and log them that'd be pretty awesome, with breaks in between.
Re:Ask HN: Could you share your personal blog here?
on Tuesday July 04, 2023 @12:03PM (#36588464)
https://auralie.substack.com/
Haven't written a lot yet, but planning to!
Re:Scores decline again for 13-year-old students in reading and mathem...
on Wednesday June 21, 2023 @04:31PM (#36423979)
I have a brother who's 13 years old.
Before the pandemic, he was a pretty smart kid, around the top half of his class, with an interest in learning for the sake of learning itself. During the pandemic, classes happened online(microsoft teams) and almost all his friends were playing video games while teaching was ongoing and disconnecting if asked a question(Not chastising him here, I did this too at times ha!)
Back to school, he's been struggling with simple algebra and geometry, which should have been clear(in a normal scenario) a year ago. The desire to learn, has been replaced with other more short-term pleasures like watching yt,gaming etc. School teachers are ill-equipped to address this but thats a tangent I'll not go off right now.
My parents have hired a private tutor for math to help him address the struggles he's facing right now, because the school sure as hell wont.
Cyberattack Hits US Lab Contractor, Nuclear Waste Site
Re:Pricing Money: A Beginner's Guide to Money, Bonds, Futures and Swaps
on Friday June 16, 2023 @04:43PM (#36363562)
> On the other hand, if he's a good farmer, and the farm produces well, and he doesn't over-extend his risk on what he's committing to, he now has a fixed price contract for his goods, which isn't going to fluctuate based on time (assuming the contract is honoured - if he's worried about that, Jeremy could then buy insurance on the risk of a default on the contract
So basically a third party would step in to assure him that he'd be paid the fixed price for a small fee? Are there no repercussions if the contract isnt honored?