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Kalanos

such hypocrisy because free speech is always their excuse not in intervene in algorithms
Re:Google AI gets cagey when asked who won the 2020 elections on Wednesday October 28, 2026 @05:37PM (#50281256)
Confirmed from within US. Everyone run the query and downvote the response.
Re:Apple introduces the new 14‑inch MacBook Pro with M6 on Tuesday October 27, 2026 @01:53PM (#50263095)
i wonder if it has 2 fans
this should not be surprising. alphafold is supervised learning.
how can i play multiplayer online?
Inform but also misinform
Re:We're working on a new RuneScape MMO on Sunday October 04, 2026 @08:54AM (#49953510)
Runescape... Forever?
Re:The DeepMind Institute on Wednesday September 16, 2026 @04:49PM (#49732806)
so glad they spun out a non-profit!
where exactly are you going to grow cocaine? on the cartel's land?
the real war the US should be fighting
What's crazy is how long it takes to report something like this to a big company and actually have them take action on it. I remember 10 years ago I reported a Giphy ad for the same thing, and it took them months to take action.
Re:The next chapter of our AI momentum on Wednesday August 05, 2026 @05:02PM (#49188951)
Gemini has been improving by what feels like 1% every week
Re:Learning a few things about running SQLite on Saturday July 18, 2026 @08:36PM (#48963870)
I tried WAL, but like you said, it froze up during multiple writes (when creating records, not updating). I guess what I needed was a write queue - not sure if that exists.
Re:Learning a few things about running SQLite on Saturday July 18, 2026 @08:30PM (#48963839)
sharding locally defeats the purpose of sharding; splitting it up across machines to get more resources
Re:Learning a few things about running SQLite on Friday July 17, 2026 @04:23PM (#48951878)
It's great! However, it's only meant for local systems. Once you need to connect over a network or robustly handle simultaneous requests, you need something like postgres.
Re:Primate Is the Last Great Web Framework on Wednesday July 15, 2026 @01:28PM (#48924257)
It's an MVC that handles realtime frontend without React?
Please refer to this as GenAI
Re:Ask HN: I underestimated how lonely building solo can be on Sunday November 09, 2025 @12:58PM (#45867533)
Good idea. Previously, I joined a python slack community and it helped a lot
pypi put out a survey a while back that was full of bs questions about dei fluff. the lack of subject matter made me really question the competence of the project staff.
Re:Are We Chasing Language Hype over Solving Real Problems? on Monday September 22, 2025 @08:22PM (#45341371)
Yes! Why is every company hiring for LLM talent? Companies that have no business doing so. They probably don't even know that supervised machine learning exists.
In the US, there is no male test for HPV
Re:'Click-to-cancel' rule is blocked on Friday July 11, 2025 @10:22AM (#44532484)
"FTC made a procedural error by failing to come up with a preliminary regulatory analysis, which is required"
Re:Google DeepMind Releases AlphaGenome on Friday June 27, 2025 @09:52AM (#44396819)
The functional predictions related to "non-coding" variants are big here. Non-coding regions, referred to as the dark genome, produce regulatory non-coding RNA's that determine the level of gene expression in a given cell type. There are more regulatory RNA's than there are genes. Something like 75% of expression by volume is ncRNA.
Re:We’re secretly winning the war on cancer on Wednesday June 11, 2025 @10:49AM (#44248246)
Despite an aging population
No. Pharma acquires these gov-funded companies. The gov de-risks them for pharma.
somatic = cancer. germline = inherited.
You're right, DNA damage is just one of the types of genetic variation in cancer. There are many other structural variations that act like remixes.

"Maybe we need to start culturing and DNA testing cancers." I assure you this is being done at a massive scale.

Due to cellular stress, cancer cells disobey multi-cellular governance. They behave more like independent organisms fighting for survival, reverting to primal programming.

Re:Preview: Amazon S3 Tables and Lakehouse in DuckDB on Tuesday March 18, 2025 @01:23PM (#43402059)
Haven't tried it. S3 Tables sounds like a great idea. However, I am wary. For it to be useful, a suite of AWS services probably needs to integrate with it. These services are all managed by different teams that don't always work well together out of the box and often compete with redundant products. For example, configuring SageMaker Studio to use an EMR cluster for Spark was a multi-day hassle with a lot of custom (insecure?) configuration. How is this different from other existing table offerings? AWS is a mess.

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