GenericThrow123
GenericThrow123 on Hacker News
Re:A new form of brain stimulation relieved severe depression in a sma...
on Tuesday April 07, 2020 @11:13AM (#22803943)
Full paper on biorxiv! https://www.biorxiv.org/content/10.1101/581280v3.full.pdf
Re:A new form of brain stimulation relieved severe depression in a sma...
on Tuesday April 07, 2020 @11:05AM (#22803852)
These incredible numbers will almost certainly drop in larger trials and once more medication resistant participants are included in a study. ECT is comparable to the efficacy of this small scale trial, but their novel approach and increased dosage could yield a major improvement to TMS.
Also, here's the biorxiv link to the full study: https://www.biorxiv.org/content/10.1101/581280v3.full.pdf
Re:A new form of brain stimulation relieved severe depression in a sma...
on Tuesday April 07, 2020 @10:52AM (#22803726)
A 90% response rate is in-line with ECT on non-medication resistant patients, actually, and it's not historically out of place that TMS performs so effectively. [1] [2]
Historically, TMS has had lower response rates than ECT, though this trial seems to offer a less invasive treatment with a comparable response rate. The measured response rates of the initial trials tend to drop after testing in a larger population, but it's great to see TMS progressing with improvements identified regularly.
1: https://www.nejm.org/doi/full/10.1056/NEJM199303253281204