I simply don't have time for that on a day to day basis where I need my machines to just work. I need it to work to the extend that I now have a base machine running Windows and with VMWare Workstation installed. All production work is done inside a VM with daily snapshots so I can always go back to before it was broken, and then tackle the issue when I have time for it. If my machine suddenly goes up in smoke, I can restore my production machines on another machine. I never have more downtime than buying a new machine, installing VMWare WS, and restoring my VMs results in.
My biggest problem was multiple monitors. The setup was, and still is, an absolute pain to get working properly with difference screen size and dynamic docking/undocking of a laptop.