I would still be concerned that a 'trivial' exploit in another browser, that would normally not lead to exploitation could cause a problem. For example user tricks chrome in to saving a file in a non-standard place, Explorer reads file and executes payload while displaying preview.

"Got an attack that only works in MS Edge but victim's in Chrome? No worries, use the microsoft-edge: protocol to jump over to that browser." https://twitter.com/ericlaw/status/622157163398430720