Not really. You generally want to use a mooring instead of an anchor. A mooring is a permanently installed anchor with a chain attached to it and a buoy on the surface. You drive your boat up and tie to the buoy. The mooring is generally rented by a marina or yacht club. The anchor is just not secure enough to leave your boat unattended on. I leave my boat on a mooring through hurricanes.

You also need to be able to get on and off your boat, so having a dock to tie up a little dinghy or having a launch (kind of like a water taxi) is key, and marinas/yacht clubs will have those facilities.

I pay around $800 a year for my mooring rental and having the gear pulled off it and inspected annually, and launch service is included. It is far cheaper than a dock.

Some other practical limitations, if you aren't at a dock you need a generator running for power. If you aren't at a dock I really have no idea how you get internet.

But, having lived on a boat in the past I would absolutely love to do it for work in the future.