One thing that seems to be missed in, at least, formulating the problem of origin of life, is that cells don't reproduce themselves. No living organism reproduces itself. Cells split into two different cells and the mother cell ceaces to exist. What it's reproduced is the suite of processes that make possible the existence and multiplication of a certain kind of complex entities, what we call living organisms. It's processes themselves that pose the problem.

And thing is that laws of physics don't have it in themselves to give birth to processes when by 'process' we mean something more in line of a function, something that would not allow us to say that the Sun is a living organism, although there's processes happening inside a star.