Same thing here. At work my host OS has nearly nothing installed on it, with an unusual toolbar and background color to remind me I'm not on the "right" machine.

I do all of my work in a VM, and as my org gets new machines, I xcopy the VHD over with minimal downtime. Full screen remote desktop is fine. My work is generous with hardware dollars, so I'm not really in any need of more memory or disk space.

That said, my work doesn't really involve anything involving lots of screen drawing. Video sucks through remote desktop (audio/video de-sync or rdp connection drops), so if I need to watch a video (presentation or youtube), I either suffer through it or do that on the host machine.