A negative area to avoid in the discussion would be the computing analogy that having computing as a hobby is a complete waste of time because a brand new CPU fab line costs in the billions and uses all kinds of non-garage compatible toxic chemicals, or the standard automotive analogy that no one can or should be a gearhead because so few living rooms have space for a supercomputer cluster to do finite element analysis and fluid dynamics simulations.

I predict long term that bio will be much like electronics or ham radio where the population drops by maybe half at each tier or level, but there sure are a lot of people at lower levels of the hobby...