This late in Python 2.7's life the changes being made are mostly fixes for esoteric bugs. One exception is the SSL module, which gets special treatment due to its importance for security. It has gained a new feature in this release (ALPN, necessary for supporting HTTP/2), and RC4 has been removed from the default cipher list.
https://hg.python.org/cpython/raw-file/v2.7.10/Misc/NEWS
(Unfortunately, there doesn't appear to be a short summary of the most important changes/bugfixes, like there have been for some of the earlier releases.)