"Oh god, syntactically significant white space!"
Python feels a bit like a toy Lisp with all the adult parts hidden.
I'm not really speaking for LISP, but in my projects what really bothers me are people that don't have common sense when indenting / formatting their code and so they start using IDE or build plugins, using common conventions and formatters that will never be able to understand the meaning of the code being formatted, making a total mess of other people' carefully crafted code. And we go round and round on this.
I don't advocate writing cryptic code. Of course I prefer code that is easy to read. That's a major basis for my opinions on syntax.
Do you think Python's syntax is cryptic and hard to read, because of the lack of end parens? Or did you just misunderstand my point completely?