> Most common adverse events consisted of chills, headache, fever, asthenia, injection-site pain, nausea, and vomiting. This safety profile is in agreement with those previously reported.8-11 However, one patient who achieved a very high anti-EGF antibody response together with a significant decrease in EGF concentration in sera developed a skin rash. After vaccination, this patient achieved a complete tumor remission, still sustained 44 months after random assignment.
> Most common adverse events consisted of chills, headache, fever, asthenia, injection-site pain, nausea, and vomiting. This safety profile is in agreement with those previously reported.8-11 However, one patient who achieved a very high anti-EGF antibody response together with a significant decrease in EGF concentration in sera developed a skin rash. After vaccination, this patient achieved a complete tumor remission, still sustained 44 months after random assignment.