Have you tried the Hadley Universe? Seriously there isn't a data set that Python can do that R can't (Lots of ways to do things as opposed to Python's one correct way). Using dplyr has been a huge change in the way I do any data munging. Panda's has started using some of dplyr with new function assign. Dplyr really handles large data sets well like data.tables (data.table is fast and handles larger sets but I like dplyr's syntax more)

By the way i should have stated that Python is a good choice for doing Data Science it is just that R works better for me.