After I started getting used to using tmux, I found that my workflow naturally separated between things I'm doing on my terminal and things that require X (like my browser). These days I use a separate workspace for X apps and terminal (occasionally moving them around).
To make my life easy, I've added xmonad-like key bindings and window layout to tmux. Since other people are sharing:
https://github.com/ygt-mikekchar/dotfiles/blob/taka/home/.tm...
I often work while travelling and when I'm on the road I often don't bother cranking up X -- just work in the Linux console. Using tmux I barely notice a difference in my workflow and it helps extend the battery.
For anyone wondering you can achieve above by typing tmux new-session -t and giving it number/name of your current session.
Also there are minor things that are nice. Like if you need to open another terminal instance in the same directory as you're currently in.