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Re:Pause Me – Apply the 20-20-20 rule to prevent eyestrain w... by brainyz on Monday April 20, 2015 @04:52AM (#9406839)
There is also a Chrome App called Eye Care. It has slightly more flexibility and runs on Win/Mac/Linux

https://chrome.google.com/webstore/detail/eye-care/ingonfahm...

+1 for f.lux

Re:Pause Me – Apply the 20-20-20 rule to prevent eyestrain w... by giraj on Monday April 20, 2015 @07:25AM (#9407292)
Another alternative is Melatonin[1] which tries to imitate f.lux for chrome(book) users.

[1] https://giraj.github.io/melatonin