One thing that was pointed out to me once was that a normal person on a vacation will spend more money in the local economy than they would otherwise donate.

Spending $500 on a plane ticket and then spend $500 at local restaurants, vendors, and accommodations won't do as much good as the $1000 would straight-up donated, but it's better than the $100 I would _actually_ donate. Don't make perfect the enemy of good.

And ultimately, it will make me care more about wherever I visited, and prompt further donations in the future.