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Re:The Elusive Universal Web Bytecode by rikkus on Thursday March 26, 2015 @12:26PM (#9270823)
I've pondered this a couple of times. One Ask HN I posted: https://news.ycombinator.com/item?id=6773980

A reply to a comment I made on another post says that the CLR and JVM suffer from GC pauses, which would not be acceptable for web apps.

Re:The Elusive Universal Web Bytecode by fla on Thursday March 26, 2015 @12:39PM (#9270957)
GC pauses already occur in most JS engine. They are especially tolerable in a web app.