News for hackers. Stuff that matters.
Re:Antibiotics targeting mitochondria kill cancer stem cells... by copperx on Sunday February 08, 2015 @10:00PM (#9019548)
There are publications (2002, 2003) publications that reported similar results:

http://www.ncbi.nlm.nih.gov/pubmed/11912125

http://www.ncbi.nlm.nih.gov/pubmed/14597870

I wonder why there were few follow-up studies? or what happened to these lines of research?

Re:Antibiotics targeting mitochondria kill cancer stem cells... by 6stringmerc on Monday February 09, 2015 @09:48AM (#9021361)
Here's the quote from the abstract that I found revealing:

Finally, recent clinical trials with doxycycline and azithromycin (intended to target cancer-associated infections, but not cancer cells) have already shown positive therapeutic effects in cancer patients, although their ability to eradicate cancer stem cells was not yet appreciated.

So, the way I read it, "It's a good idea, but we haven't gotten it to work yet, even after some testing, but it's a good idea."

I've been around a few research science labs and understand the pressures on them. Getting published is good...but not sure of the provenance of this outlet.

Re:Antibiotics targeting mitochondria kill cancer stem cells... by josephpmay on Monday February 09, 2015 @02:38AM (#9020081)
Unfortunately, a lot of negative research results aren't published, so it may be the case that follow-up studies were unsuccessful.