There was an absolutely fantastic question from the audience (rms?) for Zuckerberg, followed up with a perfectly elucidated back-and-forth reparté between them (though Jessica was freaking out a bit).

The TechCrunch transcript is just a teaser, the video clip could easily turn into a meme:

  Q: Can you talk what it’s like in order to speak publicly so people don’t
     pounce on you? Seems like you’ve changed since 2006.
  A: Have I not said enough offensive stuff? Is this less interesting?
  Q: Yeah… probably less interesting (oooooh from the crowd)
  A: Maybe we need more controversial questions.