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Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by SwellJoe on Friday February 06, 2015 @06:26PM (#9012253)
So, assuming the medical industry in the developed world gets out of the way (which I don't think is a foregone conclusion...it will take years, and possibly too many resources, to bring this to market in the US for a variety of good and bad reasons related to our regulatory environment), this is potentially one of the biggest revolutionary changes in healthcare in my lifetime.

This makes detection of both viral and bacterial infections possible with very low-cost tools; the fact that it can detect both makes me believe that detecting practically any infectious disease (or at least any infectious disease that has identified biomarkers in blood, or other easily obtainable bodily fluid) is on the near horizon.

One could buy this dongle, or one like it, and new diseases could be added via software upgrades (or by in-app purchases for the diseases you want to check for). This would potentially make doctors office visits obsolete for all but serious disease and chronic conditions. No need to go get checked for strep when you have a sore throat (of course, getting the antibiotics to treat it is another regulatory hurdle people in the US would face), lower need for cities and universities to provide STD testing, though treatment and education would still likely be within their perview. It allows better self-management of HIV, hepatitis, Lyme disease, and other chronic viral illnesses through more rapid and frequent testing.

Even if this doesn't evolve to include other types of detection, I would still happily pay several hundred dollars for a re-usable STD testing tool. I like to get tested every 6 months, but the hassle and cost of going to the doctor or Planned Parenthood or online testing lab is high (free or low cost testing is available, but you trade much more hassle for the lower cost...among my friends who get tested at the city health center, they usually spend an hour or two waiting, which is not a cost I'm willing to pay to save a couple hundred bucks). If I could test for HIV for free before every new partner (and, hell, make it a practice to test with every partner), that'd be fantastic.

Another article about this was posted a week or so ago to HN, but it didn't get any comments or many upvotes, which was disappointing, as this seems like entirely revolutionary technology, to me. And, it makes me want to go into medical tech because of how huge the potential is (but it would be an entirely new field for me, so my ability to be productive in it would take a while to develop).

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by XorNot on Friday February 06, 2015 @07:40PM (#9012531)
You cannot possibly software update a device like this. The actual detection mechanics are chemical. The advance is in miniaturizing and automating tasks which used to take a laboratory and staff to do.
Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by SwellJoe on Friday February 06, 2015 @07:49PM (#9012555)
Is it? I don't know the mechanics. How about genetic testing, is that also a chemical process that is unique for each marker? Seems like a genetic sequencing tool could be programmable once the DNA/RNA has been analyzed. The best HIV test available is an RNA test, which can provide results as early as six days after exposure. This is obviously not my area of expertise, so I don't know how realistic it would be to downsize such a thing.

Also, how does this device perform a test for a viral infection and for a bacterial infection, if the tests are unique and chemical? Does it use a particular substance for each test, which has to be refilled per use? (Again, I have no idea how this stuff works.)

I know that 23andme continues to produce new information about my genes as new studies are done to find genetic markers for various diseases and traits, which is pretty cool. If there were a device that detected viral and bacterial RNA/DNA, would that be software extensible?

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by Fomite on Friday February 06, 2015 @10:33PM (#9012956)
Yes, the tests are unique and chemical. You either need bespoke antigens that will react to the presence of specific pathogens, or primers and other components for DNA/RNA based tests.

Beyond that, these testing systems probably can't manage the sensitivity and specificity of a properly run diagnostic lab. That's fine for the setting they're being considered in, because those labs don't exist, are hard to reach or can be easily overwhelmed in an outbreak, but for a developed world setting? I don't really see it. Home diagnostics for infectious diseases over a broad range of potential pathogens is a really hard technical challenge with no real payoff - you still need to go to the doctor.

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by bitCromwell on Friday February 06, 2015 @11:46PM (#9013097)
If you have accurate test results that show you need medicine and can obtain it without a gatekeeper then you don't "need" to go to a doctor. That's one hell of a payoff.
Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by Fomite on Friday February 06, 2015 @11:59PM (#9013123)
Yeah, there's no way you're getting prescription antibiotics or antivirals without seeing a doctor because "My iPhone says I have pertussis".

Lab results alone do not a medically responsible treatment plan make.

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by cdcarter on Saturday February 07, 2015 @12:10AM (#9013149)
This is the exact reason that free STD testing clinics DO NOT discuss symptoms with you, and with a positive test immediately refer you to an MD. A testing environment is not treatment or management.
Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by bitCromwell on Saturday February 07, 2015 @07:29AM (#9013781)
Its unclear who "you" means, most people on earth can actually buy antibiotics without this. Also unsure as to how you define what is "responsible" for them.
Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by Fomite on Saturday February 07, 2015 @03:46PM (#9015249)
The post at the top of this chain makes it abundantly clear we're talking about the United States.

And, as an epidemiologist, the ready availability of antibiotics without any interaction with a doctor is something I'd be pretty comfortable classifying as inherently irresponsible.

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by nakkiel on Friday February 06, 2015 @09:18PM (#9012797)
Did you read the article?

Quote from the article:

"Blood from a patient is drawn through microscopic channels where it then meets chemicals that react with HIV and syphilis antibodies to produce a color change. This can then be picked up by a set of photocells in the dongle, and the results are then sent to an app on the attached smartphone or computer."

Re:Cheap Smartphone Dongle Diagnoses HIV And Syphilis by SwellJoe on Friday February 06, 2015 @10:01PM (#9012899)
Huh...I'd read the earlier article and didn't remember seeing that explanation. I didn't read this variant of the article, as I assumed the one I saw earlier was the more authoritative source, but, perhaps this is just a better article.