Maybe. But, then I'd have to maintain the list. I used to do that, many years ago, for problem domains using a local Squid installation (my first company was based around Squid, so I already ran the local Squid 24/7), but, maintenance of the list was time-consuming. AdBlock Plus is set it and go (I occasionally have to disable it for videos of something, but it's so rare that I sometimes forget I even have it running).

I don't notice the performance or memory problems being discussed, so it's not a big deal for me. My lappy has 8GB of RAM and I've never run into memory problems. But, I guess my tablet (with only 2GB of RAM) or phone probably shouldn't run AdBlock Plus, even if it becomes available for Android. Somehow I never see auto-start audio ads on those devices. Maybe I should just figure out how to make Flash and audio behave the same on my lappy.