> I'm talking real life risks to your mental and physical health, destruction of relationships, opportunity cost, and (potentially) the vaporization of that awesome scientific career that you spent over a decade building because the one person in charge of you with no oversight decided they didn't like you.

This person's rant describes my experience reasonably well. Insomnia? Check. Neutral-at-best advising relationship? Check. Declining general health due to overwork and stress? Check. Narcissist/psychopath on my committee? Check. Know somebody who ended up in a psychiatric hospital? Check.

Check. Check. Check.

Edit: I was in a top-5 science/engineering PhD program.